Results 181 to 190 of about 10,026 (288)

Drug dissolution problems in ostomy patients: a chart review and patient interview analysis. [PDF]

open access: yesInt J Colorectal Dis
Remane Y   +9 more
europepmc   +1 more source

A Systematic Review on the Use of Intravascular Ultrasound and Optical Coherence Tomography During Femoropopliteal Endovascular Intervention

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Performing adjunctive intravascular imaging during femoropopliteal endovascular intervention could improve treatment planning and outcome. This systematic review assessed how imaging findings of intravascular ultrasound (IVUS) and optical coherence tomography (OCT) can contribute to improving treatment planning and outcomes of patients with ...
Lisa Rutten   +4 more
wiley   +1 more source

Engineering Substrate Acceptance of Resveratrol O‐Methyltransferase from Vitis vinifera for the Selective Synthesis of O‐Methyl Protected Biobased Hydroxystyrenes

open access: yesChemCatChem, EarlyView.
Reaction sequence for the synthesis of methylated products through enzymatic decarboxylation of bio‐based hydroxycinnamic acids and subsequent direct methylation of the resulting styrene intermediates without any further isolation and purification steps.
Kamela Myrtollari   +6 more
wiley   +1 more source

Oral dosage forms for drug delivery to the colon: an existing gap between research and commercial applications. [PDF]

open access: yesJ Mater Sci Mater Med
Martínez E   +7 more
europepmc   +1 more source

Studying the Ingress of Ag Nanoparticles into Imprinted Nanocavities by Nanoimpact Electrochemistry

open access: yesChemElectroChem, EarlyView.
The ingress of single silver nanoparticles (NPs) into nanocavities is studied by nanoimpact electrochemistry. The NP‐imprinted matrix approach is used to create well‐defined nanocavities that reuptake selectively silver NPs based on their size as detected by the current–time oxidation transients of single NPs.
Hila Sagi-Cohen   +2 more
wiley   +1 more source

Effect of Mild to Moderate Hepatic Impairment on Valemetostat Pharmacokinetics: An Open‐Label, Phase I Study

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Valemetostat tosylate (valemetostat) is a dual inhibitor of enhancer of zeste homolog (EZH) 2 and EZH1, approved in Japan for the treatment of relapsed/refractory peripheral T‐cell lymphoma and adult T‐cell leukemia/lymphoma. This Phase I, open‐label study evaluated the pharmacokinetics and safety of a single 50‐mg oral dose of valemetostat in
Masaya Tachibana   +8 more
wiley   +1 more source

Combined Immediate‐Release and Extended‐Release Formulation of Sodium Valproate Provides Stable Plasma Levels for Inhibition of Histone Deacetylation

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract A modified controlled‐release sodium valproate formulation (VAL001, test) was compared with an approved enteric‐coated tablet formulation (Absenor, reference). Pharmacokinetics and safety/tolerability were evaluated in healthy subjects to bridge with positive efficacy results from an early‐phase patient trial of valproate in combination with ...
Nikhil Ahuja   +8 more
wiley   +1 more source

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