Results 11 to 20 of about 10,026 (288)

Formulation study of duloxetine hydrochloride enteric-coated tablets

open access: yesSN Applied Sciences, 2023
During storage, duloxetine hydrochloride may have an unexpected cross reaction with enteric coated acrylic resin, which may affect the product quality.
Jiang Guowei   +4 more
doaj   +2 more sources

In Silico Evaluation of the Biopharmaceutical and Pharmacokinetic Behavior of Metronidazole from Coated Colonic Release Matrix Tablets [PDF]

open access: yesPharmaceutics
Background: Physiologically based biopharmaceutics modeling (PBBM) models can help to predict drug release and in vivo absorption behaviors. Colon drug delivery systems have gained interest over the past few years due to the advantages they provide in ...
Roberto Arévalo-Pérez   +2 more
doaj   +2 more sources

Evaluation of pharmacokinetics and relative bioavailability of pentoxifylline and its metabolite in beagle dogs following different formulations [PDF]

open access: yesFrontiers in Pharmacology
A single-oral-dose, two-period cross-over study with a 5-day washout period under fed condition was conducted in six beagle dogs to explore the pharmacokinetic characteristics and relative bioavailability between sustained-release (SR) tablets and ...
Yuxiang Xu   +8 more
doaj   +2 more sources

Case report: Alectinib-associated intestinal ulceration and colitis in a patient with non-small cell lung cancer and effective treatment with Mesalazine [PDF]

open access: yesPathology and Oncology Research
BackgroundAlectinib is effective in extending the survival of patients with anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC) and generally has manageable side effects.
Zijian Qiu, Fei Ke, Xiaoping Zhu
doaj   +2 more sources

Development of Enteric-coated Tablets of Sodium 4,4'-(propnadiamido)dibenzoate

open access: yesРазработка и регистрация лекарственных средств, 2022
Introduction. Enteric coat have a wide range of functions: from protecting the API from the adverse effects of the acidic environment of the stomach to targeted delivery to certain parts of the intestine in order to increase the effectiveness of the drug.
Ju. M. Kotsur   +2 more
doaj   +1 more source

Development of Duloxetine Hydrochloride Tablets for Delayed and Complete Release Using Eudragit L 100

open access: yesInternational Journal of Polymer Science, 2021
The purpose of the research was to optimize the preparation of duloxetine hydrochloride (duloxetine HCl) delayed release tablets. Duloxetine HCl produces a toxic substance called alpha-naphthol when duloxetine HCl is in contact with gastric fluid.
M. Yasmin Begum   +6 more
doaj   +1 more source

Characterization of enteric-coated erythromycin tablets by Raman mapping and its pharmaceutical evaluation

open access: yesFrontiers in Chemistry, 2023
Enteric tablet coating thickness is a critical quality attribute of the coating process that can affect dissolution behavior in vitro as well as release in vivo.
Wenbo Zou   +3 more
doaj   +1 more source

Oral Delivery of Niclosamide as an Amorphous Solid Dispersion That Generates Amorphous Nanoparticles during Dissolution

open access: yesPharmaceutics, 2022
Niclosamide is an FDA-approved anthelmintic that is being studied in clinical trials as a chemotherapeutic and broad-spectrum antiviral. Additionally, several other applications are currently in the preclinical stage.
Miguel O. Jara   +7 more
doaj   +1 more source

Effects of Yunnan Baiyao retention enema combined with mesalazine enteric-coated tablets and bifidobacterium triple viable capsules for treating ulcerative colitis

open access: yes结直肠肛门外科, 2022
[Objectives] To determine the effects of Yunnan Baiyao retention enema combined with mesalazine enteric-coated tablets and bifidobacterium triple viable capsules for treating ulcerative colitis (UC).
Liu Junjie, Gao Jian, Li Shuling
doaj   +1 more source

Formulation and development of Serratiopeptidase enteric coated tablets and analytical method validation by UV Spectroscopy

open access: yesInternational Journal of Analytical Chemistry, 2021
Serratiopeptidase (SRP) is a proteolytic enzyme that emerged as one of the most potent anti-inflammatory and analgesic drugs. The purpose of the present study was to formulate and evaluate enteric-coated tablets for SRP and investigate their stability ...
Vijay Kumar Panthi   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy