Results 41 to 50 of about 4,397 (241)

A pharmacokinetic and pharmacodynamic comparison of plain and enteric‐ coated prednisolone tablets. [PDF]

British Journal of Clinical Pharmacology, 1992
1. Eight healthy volunteers and eight patients suffering from chronic obstructive pulmonary disease (COPD) received 30 mg prednisolone as plain (P) and enteric‐coated tablets (EP) in a randomised, cross‐over manner. Plasma prednisolone and cortisol and blood glucose were measured over 24 h. 2. Although absorption of prednisolone was considerably slower
Adair, C.G., Mccallion, O., McElnay, James, Scott, M.G., Hamilton, B.A., Mccann, J.P., Stanford, C.F., Nicholls, D.P.   +7 more
openaire   +3 more sources

Quality by Design Applied Development of Immediate-Release Rabeprazole Sodium Dry-Coated Tablet

Pharmaceutics, 2021
The aim of this study was to develop immediate-release oral rabeprazole sodium tablets with rapid efficacy and gastric stability for the treatment of gastroesophageal reflux disease.
Sang-Ho Lee, Joo-Eun Kim
doaj   +1 more source

Thermally Induced Gelling Systems Based on Patchy Polymeric Micelles

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
A novel strategy to design thermally induced gelling systems with tunable material properties is reported. Polymeric mixed‐shell micelles displaying multiple thermosensitive patchy domains formed hydrogels by assembling into well‐entangled worm‐like network structures upon heating to body temperature. The patchy micelle design significantly affects the
Binru Han, Shota Fujii, André J. van der Vlies, Masoud Ghasemi, Joshua T. Del Mundo, Sarah N. Kiemle, Esther W. Gomez, Enrique D. Gomez, Ralph H. Colby, Urara Hasegawa   +9 more
wiley   +1 more source

Ameliorative Effects of Selenium-Containing Proteins and Peptides from Selenium-Enriched Cardamine L. against Ulcerative Colitis in Mice [PDF]

Shipin Kexue
Objective: To assess the mitigative effects of plant-derived organic selenium on ulcerative colitis (UC). Methods: Selenium-containing proteins (SePro) and peptides (SePP) were prepared from natural selenium-enriched Cardamine L.
MENG Yao, HE Ziyan, LUO Ying, ZHANG Zhong, LI Jianke, YUAN Li
doaj   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

The Synergy of Artificial Intelligence and 3D Bioprinting: Unlocking New Frontiers in Precision and Tissue Fabrication

Advanced Functional Materials, EarlyView.
Advances in integrating artificial intelligence into 3D bioprinting are systematically reviewed here. Machine learning, computer vision, robotics, natural language processing, and expert systems are examined for their roles in optimizing bioprinting parameters, real‐time monitoring, quality control, and predictive maintenance.
Joao Vitor Silva Robazzi, Irem Deniz Derman, Deepak Gupta, Logan Haugh, Yogendra Pratap Singh, Vaibhav Pal, Yasar Ozer Yilmaz, Suihong Liu, Andre Luis Dias, Rogerio Andrade Flauzino, Ibrahim Tarik Ozbolat   +10 more
wiley   +1 more source

Development of a particle swarm optimization-backpropagation artificial neural network model and effects of age and gender on pharmacokinetics study of omeprazole enteric-coated tablets in Chinese population

BMC Pharmacology and Toxicology, 2022
Background The effects of age and gender were explored on pharmacokinetics study of omeprazole enteric-coated tablets in Chinese population and a plasma concentration prediction model was developed.
Yichao Xu, Jinliang Chen, Dandan Yang, Yin Hu, Bo Jiang, Zourong Ruan, Honggang Lou   +6 more
doaj   +1 more source

Towards High‐Acuity Vision Restoration: Hybrid Retinal Prosthesis Composed of a High‐Density Multielectrode Array Integrated With Glutamatergic Cells

Advanced Functional Materials, EarlyView.
This work introduces a novel Hybrid Retinal Implant (HRI), composed of a high‐density electrode array integrated with glutamatergic neurons to overcome key limitations of current retinal prostheses. The significant reduction of activation threshold and of electrode cross‐talk yields in an improved spatial resolution.
Nairouz Farah, Amos Markus, Gal Shpun, Yoav Chemla, Erel Lasnoy, Tamar Azrad‐Leibovitch, Fikre Fentahon, Zeev Zalvesky, Yossi Mandel   +8 more
wiley   +1 more source

Decreasing cardiovascular morbidity: how to improve adherence to the treatment in the translational era

Терапевтический архив, 2020
Cardiovascular diseases are the main drivers of the morbidity and mortality in Russian Federation. We briefly discussed the poor adherence of the patients and outlined the solutions of this problem.
I. V. Zhirov
doaj   +1 more source

Single Solid‐State Ion Channels as Potentiometric Nanosensors

Advanced Functional Materials, EarlyView.
Single gold nanopores functionalized with mixed self‐assembled monolayers act as solid‐state ion channels for direct, selective potentiometric sensing of inorganic ions (Ag⁺). The design overcomes key miniaturization barriers of conventional ion‐selective electrodes by combining low resistivity with suppressed loss of active components, enabling robust
Gergely T. Solymosi, Gyula Jágerszki, Levente Illés, Péter Fürjes, Róbert E. Gyurcsányi   +4 more
wiley   +1 more source