Results 71 to 80 of about 10,026 (288)

Investigation for the quality factors on the tablets containing medicated pellets [PDF]

, 2015
Sustained and controlled pellets are considered as one of the ideal dosage forms. Due to the large coverage area of pellets, loaded drugs can be absorbed completely in the body and bioavailability is improved correspondingly.
Hu, Jingbo, Tan, Xueying
core   +3 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Enteric coating of ibuprofen tablets (200 mg) using an aqueous dispersion system

Brazilian Journal of Pharmaceutical Sciences, 2010
Ibuprofen is a propionic acid derivative that belongs to the class NSAIDs. Major adverse reactions associated with Ibuprofen are related to GIT and include peptic and mucosal ulcers, dyspepsia, severe gastric pain and bleeding, that results in excessive ...
Rabia Bushra, Muhammad Harris Shoaib, Nousheen Aslam, Zafar Alam Mehmood, Durriya Hashmat   +4 more
doaj   +1 more source

Advanced Oral Delivery Systems for Nutraceuticals

Advanced Healthcare Materials, EarlyView.
Emerging delivery technologies are explored to overcome barriers to oral nutraceutical absorption. Traditional carriers are compared with novel platforms including biodegradable polymers, MOFs, MPNs, and 3D printing. These systems enhance bioavailability, control release, and enable personalized nutrition.
Xin Yang, Linzixuan Zhang, Zhiling Zheng, Robert Langer, Ana Jaklenec   +4 more
wiley   +1 more source

Patient-centred pharmaceutical design to improve acceptability of medicines : similarities and differences in paediatric and geriatric populations [PDF]

, 2014
Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are ...
Batchelor, Hannah K., Ernest, Terry B., Flanagan, Talia, Liu, Fang, Orlu-Gul, Mine, Ranmal, Sejal, Thomas, Iwan W., Tuleu, Catherine   +7 more
core   +3 more sources

Permeation Enhancer‐based Ionogel Shows Remarkable Potential for Oral Insulin Delivery

Advanced Healthcare Materials, EarlyView.
This study proposes a novel formulation of decanoate in an ionic liquid inspired drug delivery system. The formulation demonstrates ideal physicochemical and material properties for oral peptide delivery. Findings indicate that choline decanoate (1:2 molar ratio) forms a viscoelastic gel that enables high oral bioavailability of insulin in rats ...
Konstantinos Raptis, Joanne Heade, Cristiana Cunha, Marco van de Weert, Lasse Saaby, Stine Rønholt, Hanne Mørck Nielsen   +6 more
wiley   +1 more source

Effects of thickened drinks on the disintegration of various oral tablets

Heliyon, 2020
Food thickeners are widely used to aid the oral administration of medications to patients with dysphagia. Powder-type food thickeners are used to modulate the viscosity of therapeutic solutions depending on the swallowing capacity of patients.
Taisuke Matsuo, Chinatsu Sato, Takashi Tomita, Yasuyuki Sadzuka   +3 more
doaj  

Preformulation Studies for Generic Omeprazole Magnesium Enteric Coated Tablets

BioMed Research International, 2015
Preformulation is an important step in the rational formulation of an active pharmaceutical ingredient (API). Micromeritics properties: bulk density (BD) and tapped density (TD), compressibility index (Carr’s index), Hauser’s ratio (H), and sieve analysis were performed in order to determine the best excipients to be used in the formulation development
M. Ratansi, Godeliver A.B. Kagashe, Eliangiringa Kaale, C. O. Migoha   +3 more
openaire   +3 more sources

Biofabrication of a Filtration Barrier by Integrating Electrospun Membranes and Flow in a Glomerular Co‐Culture

Advanced Healthcare Materials, EarlyView.
An ex vivo glomerular filtration barrier is engineered using electrospun, biomimetic membranes seeded with human glomerular cells. The model supports fenestrated endothelium and podocyte foot processes under flow, mimics size‐selective filtration, and enables disease modeling with hiPSC‐derived podocytes, offering a powerful platform for studying ...
Camilla Mussoni, Anna Rederer, Vladimir Stepanenko, Frank Würthner, Philipp Stahlhut, Jürgen Groll, Mario Schiffer, Taufiq Ahmad, Janina Müller‐Deile   +8 more
wiley   +1 more source

Evaluating and optimizing oral formulations of live bacterial vaccines using a gastro-small intestine model [PDF]

, 2016
Gastrointestinal (GI) models that mimic physiological conditions in vitro are important tools for developing and optimizing biopharmaceutical formulations. Oral administration of live attenuated bacterial vaccines (LBV) can safely and effectively promote
Adele Costabile, Alexander D. Edwards, Brenneman, Chen, Cook, de Barros, Dimitrios Charalampopoulos, Duan, Edwards, Edwards, Edwards, Granato, João M.S. de Barros, Levine, Levine, Levine, Macfarlane, Macfarlane, Mahbubani, Mainville, Medina, Molly, Morgan, Ozturk, Ratanasuwan, Sander, Sannasiddappa, Siepmann, Vitaliy V. Khutoryanskiy   +28 more
core   +1 more source