Discuss the Rationale for Minimally Invasive Endodontics and the Merits and Demerits of the Concept
ABSTRACT Minimally invasive endodontics (MIE) places emphasis on the conservation of sound tooth structure and viable pulp tissue during endodontic procedures such as root canal treatment (RCTx) and vital pulp therapy (VPT). The use of minimal access cavity designs and conservative canal preparation dimensions have been investigated as a way to improve
Iris Mohan Li
wiley +1 more source
Comparative Effectiveness of Mycophenolate Mofetil and Tacrolimus as a Second-Line Therapy for Autoimmune Hepatitis: A Systematic Review and Meta-Analysis. [PDF]
Almalki F +13 more
europepmc +1 more source
Adenosine—A Regulator of Human Testicular Peritubular Cells
ABSTRACT Background Extracellular purines, in particular ATP and adenosine, are regulators of physiological and pathophysiological processes throughout the human body. Roles in the human testis are emerging and include actions on peritubular cells, which form the wall of seminiferous tubules.
Lina Scholz +12 more
wiley +1 more source
Managing Delayed or Missed Doses of Prolonged-Release Tacrolimus in Transplant Recipients: Implications for Drug Exposure and Recovery Strategies. [PDF]
Arraki Zava S +6 more
europepmc +1 more source
Summary Comparative data on reduced‐dose (8 Gy) versus standard‐dose (12 Gy) total body irradiation (TBI) before allogeneic haematopoietic stem cell transplantation (allo‐HSCT) for adults with acute lymphoblastic leukaemia (ALL) remain limited. We retrospectively analysed 101 adults undergoing first allo‐HSCT between 1999 and 2024 after 8 Gy or 12 Gy ...
Isabella Gruber +7 more
wiley +1 more source
Early Relapse Frequency as a Potential Predictor of Generalization in Ocular Myasthenia Gravis: A Case Report. [PDF]
Terai J +3 more
europepmc +1 more source
Non‐canonical PKG1 regulation in cardiovascular health and disease
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley +1 more source
Post-Transplant Cyclophosphamide Improves Survival in HLA-DPB1 Mismatched Unrelated Donor Allogeneic Transplantation. [PDF]
McCurdy SR +19 more
europepmc +1 more source
As a metabolically versatile organ, the heart is capable of generating energy from a wide range of substrates. Although fatty acid and glucose metabolism in the heart have been extensively studied, the contribution of amino acid metabolism to cardiac physiology and disease is gaining increasing attention.
Tayyiba Azam +6 more
wiley +1 more source
Chlorella for health: evidence from a GRADE-assessed systematic review and dose-response meta-analysis. [PDF]
Jafari A +4 more
europepmc +1 more source

