This review outlines the potential role of anti‐GPCR autoantibodies in MASLD/MASH, given their involvement in a wide range of diseases and their possible contribution to MASLD/MASH pathophysiology. We also focused on anti‐ApoA1 autoantibodies, sharing functional features with anti‐GPCR autoantibodies and have been shown to promote liver steatosis in ...
Sabrina Pagano+3 more
wiley +1 more source
Abundance and composition data of microbiomes in agricultural biogas plants of Lower Saxony, Germany, with variation in organic substrates, process parameters and nutrients. [PDF]
Krause SMB+5 more
europepmc +1 more source
Abstract In this paper, we explore the unintended consequences of parenting support and child protection services for families who have migrated from Vietnam to Berlin, Germany. We identify such negative consequences on three levels: The relationship between practitioners and parents was, contrary to good intentions, often characterized by tensions and
Nga Thi Thanh Mai, Gabriel Scheidecker
wiley +1 more source
Sex alters thyroid hormone's effect on protein O-GlcNAcylation in the aged mouse heart. [PDF]
Olson AK, Zhu WZ, Ledee D.
europepmc +1 more source
The Economic Consequences of Social Unrest: Evidence from Initial Public Offerings
ABSTRACT Prior research attributes negative stock market performance following episodes of social unrest to elevated uncertainty. However, social unrest does not solely increase uncertainty but separately acts to decrease investor sentiment. To determine which effect dominates, we study initial public offering (IPO) underpricing, which responds ...
Philip Barrett+2 more
wiley +1 more source
Comprehensive Insights into Keloid Pathogenesis and Advanced Therapeutic Strategies. [PDF]
Kim HJ, Kim YH.
europepmc +1 more source
Enhancing endocannabinoid signaling by targeting FAAH effectively mitigates cognitive deficits, reduces amyloid pathology, and modulates neuroinflammatory responses in a preclinical model of Alzheimer's disease. This effect is potentially mediated by attenuating the Aβ‐induced overexpression of the Bace1 gene through CB1‐dependent hypermethylation of ...
Sergio Oddi+12 more
wiley +1 more source
SNP and Structural Study of the Notch Superfamily Provides Insights and Novel Pharmacological Targets against the CADASIL Syndrome and Neurodegenerative Diseases. [PDF]
Papageorgiou L+12 more
europepmc +1 more source
Reactive oxygen species induce mutagenic DNA lesions, such as 8‐oxo‐2′‐deoxyguanosine (8‐oxodG), which acts as a template for dCMP and dAMP incorporation through its anti and syn conformations. Specific residues must regulate the fidelity of templated 8‐oxodG.
Noe Baruch‐Torres+10 more
wiley +1 more source
Natural Bioactive Compounds in the Management of Type 2 Diabetes and Metabolic (Dysfunction)-Associated Steatotic Liver Disease. [PDF]
Ciobârcă D+5 more
europepmc +1 more source