Results 121 to 130 of about 149,534 (308)

Fully Reversible Regulation of 8‐17 DNAzyme Activity Using Nucleoside‐Based Diarylethenes

open access: yesChemistry – A European Journal, EarlyView.
The site‐specific incorporation of nucleosidic diarylethenes into the 8–17 deoxyribozyme (DNAzyme) identified position 2.1 as optimal. Compound dU‐PhtBu enabled efficient light‐dependent control of catalytic activity, while maintaining thermal stability and reversibility.
Jörn Bargstedt   +3 more
wiley   +1 more source

Impact of Distillation Column Design on Potential for the Integration of Mechanical Vapor Recompression

open access: yesChemie Ingenieur Technik, EarlyView.
Mechanical vapor recompression integration in distillation is analyzed, focusing on feed preheating and column pressure drop. Binary methanol–water and benzene–toluene separations are studied to identify optimal designs, which are further assessed in a bioethanol vacuum distillation sequence regarding energetic, ecological, and economic performance ...
Thorben Hochhaus   +3 more
wiley   +1 more source

Functional Characterization of the 4 groups (SHAM, TAC, TAC+MET, and TAC+SalB mice) at 2 weeks after TAC surgery.

open access: yes, 2016
(A) Representative echocardiograms used to measure the LV wall thickness during cardiac cycles. (B) AoPg (C) LVPWd (D) EF (E) FS measured by echocardiography were compared among the SHAM (n = 10),TAC(n = 9),TAC+MET(n = 9), and TAC+SalB (n = 9) groups ...
Yafang Tan (113219)   +6 more
core   +1 more source

Matching Heat Pump Configurations and Process Parameters for Cost‐Minimal Heat‐Integrated CO2 Capturing Process

open access: yesChemie Ingenieur Technik, EarlyView.
In a CO2 absorption process, it is investigated whether the adjustment of operating parameters facilitates the integration of different closed heat pump cycles considering various refrigerants. The influence of different integration concepts and electricity prices are investigated by means of resulting total annual costs.
Johannes Wloch   +2 more
wiley   +1 more source

Example cerebellar cortex TAC, arterial ROI TAC and estimated AIF (A); comparison of PET measured TAC and model estimated TAC for the arterial ROI (B).

open access: yes, 2015
Example cerebellar cortex TAC, arterial ROI TAC and estimated AIF (A); comparison of PET measured TAC and model estimated TAC for the arterial ROI (B).
Yi Su (311753)   +7 more
core   +1 more source

A Systematic Review on Disease‐Modifying Therapies in Parkinsonian Disorders

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Parkinsonian disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, and progressive supranuclear palsy, are progressive neurodegenerative conditions with no treatment options to slow disease progression. This systematic review provides an overview of evidence of disease‐modifying therapies that have been evaluated in ...
Pepijn P.N.M. Eijsvogel   +3 more
wiley   +1 more source

CAT 2008 Post-Tournament Evaluation: The Mertacor’s Perspective

open access: yes, 2009
TAC Market Design (or CAT) tournament is an effort to study the competition among modern stock exchanges trying to attract potential traders while maximizing their profit.
Mitkas, Pericles A.   +1 more
core  

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor   +12 more
wiley   +1 more source

The double powerlocale and exponentiation: A case study in geometric logic [PDF]

open access: yes, 2004
If X is a locale, then its double powerlocale PX is defined to be PU(PL(X)) where PU and PL are the upper and lower powerlocale constructions. We prove various results relating it to exponentiation of locales, including the following.
Vickers, Steven
core  

Heterozygous Med13l mice recapitulate a developmental growth delay and craniofacial anomalies seen in MED13L syndrome

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Gene transcription is crucial for embryo and postnatal development and is regulated by the Mediator complex. Mediator is comprised of four submodules, including the kinase submodule (CKM). The CKM consists of MED13, MED12, CDK8, and CCNC.
Anna K. Leinheiser   +5 more
wiley   +1 more source

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