Non‐canonical PKG1 regulation in cardiovascular health and disease
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
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Transcranial alternating current stimulation can disrupt or reestablish neural entrainment in parkinsonian motor cortex. [PDF]
Tran H +11 more
europepmc +1 more source
The Relationship Between Polycystic Ovary Syndrome (PCOS) and Depression
ABSTRACT Objective Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder, frequently accompanied by psychological comorbidities including depression. The aim of this narrative review is to summarise the latest research regarding potential contributors to and underpinning mechanisms of this relationship.
Asimina I. Karampela, Maralyn Druce
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Transcranial Alternating Current Stimulation for Pain: Mixed Evidence and the Path to Precision Neuromodulation. [PDF]
Fathi Y +4 more
europepmc +1 more source
Our study demonstrated that TGF‐β1 activated MAPK signalling pathway and promoted the MMT and secretion of CCL17 under CD‐associated intestinal inflammatory conditions. AMSC‐sEVs can deliver MFGE8, which inhibits MMT and CCL17‐mediated Treg recruitment by suppressing the MAPK signalling pathway, thereby alleviating intestinal fibrosis.
Minghao Xie +6 more
wiley +1 more source
Implementation and early outcomes of a team science consultation service: Addressing key challenges in translational research collaborations. [PDF]
Lee SS +10 more
europepmc +1 more source
Gamma tACS over the prefrontal and parietal cortices enhances episodic memory performance. [PDF]
Honma K, Nomura T.
europepmc +1 more source
ABSTRACT Background Acute kidney injury (AKI) is a frequent and clinically relevant complication in allogeneic hematopoietic cell transplantation (HCT) recipients, particularly during the early post‐HCT period. Although AKI has been extensively reported in long‐term follow‐up studies, data focusing on the initial hospitalization phase remain limited ...
Luiz Carlos da Costa‐Junior +10 more
wiley +1 more source
Effects of 40 Hz transcranial alternating current stimulation on neural synchronization and cognitive correlates in schizophrenia: An EEG study. [PDF]
Liu Y +11 more
europepmc +1 more source
Advancing Ecological Understanding and Sustainable Management of Small Pelagic Fish
ABSTRACT Small pelagic fish (SPF) are critical to the trophodynamic structure and function of marine systems and support some of the most valuable and socially important fisheries worldwide. Their “boom and bust” population dynamics, shifts in distribution, and importance as forage resources for other fish stocks place unique challenges to assessing ...
Myron A. Peck +22 more
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