Results 111 to 120 of about 1,688,805 (284)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Noise suppression with high Mach number inlets [PDF]

open access: yes
Experimental results were obtained for two types of high Mach number inlets, one with a translating centerbody and a fixed geometry inlet (collapsing cowl) with no centerbody. The aerodynamic and acoustic performance of these inlets was examined.
Cherng, J. G., Lumsdaine, E., Tag, I.
core   +1 more source

“Little” Immortality: Immortological Theme in the Internet Microformats

open access: yesCorpus Mundi
This article correlates in content with the previous article in the journal. Internet microformats (short stories, gifs, pics, memes, demotivators, etc.) have a short life compared to “monumental” content, but are characterized by a high speed of ...
Artur A. Dydrov, Milena S. Vizgina
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Tree-local MCTAG with shared nodes : an analysis of word order variation in German and Korean [PDF]

open access: yes, 2004
Tree Adjoining Grammars (TAG) are known not to be powerful enough to deal with scrambling in free word order languages. The TAG-variants proposed so far in order to account for scrambling are not entirely satisfying.
Kallmeyer, Laura, Yoon, SinWon
core   +1 more source

Elasmobranch Mark–Recapture Experiment off the Balearic Islands: Insight into Scyliorhinus canicula Growth, Mobility, and Population Size

open access: yesFishes
Despite the high diversity of elasmobranch fishes in the Balearic Islands, knowledge of their biology and population dynamics is still scarce. A recent mark-and-recapture experiment off the Balearic Islands tagged 3738 individuals of 23 shark and batoid ...
Francesca Ferragut-Perello   +7 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

A review on missing tags detection approaches in RFID system [PDF]

open access: yes, 2018
Radio Frequency Identification (RFID) system can provides automatic detection on very large number of tagged objects within short time. With this advantage, it is been using in many areas especially in the supply chain management, manufacturing and many ...
Azmi, Mohd Sanusi   +5 more
core  

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