Results 131 to 140 of about 1,405,161 (353)

On Tail Index Estimation for Dependent, Heterogenous Data [PDF]

In this paper we analyze the asymptotic properties of the popular distribution tail index estimator by B. Hill (1975) for possibly heavy- tailed, heterogenous, dependent processes.
Jonathan B. Hill
core  

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Monte Carlo-Based Tail Exponent Estimator

In this paper we study the finite sample behavior of the Hill estimator under α-stable distributions. Using large Monte Carlo simulations we show that the Hill estimator overestimates the true tail exponent and can hardly be used on samples with small ...
Jozef Barunik, Lukas Vacha
core  

Tail-sync responses.

, 2019
A: PSTHs of the AN (top, red) and GBC (bottom, blue) models driven by 500-Hz tone at 95 dB SPL (see Table 1 for the parameter values used). B-C: Level-dependent spiking rates (B) and phase-locking (C) of the same AN (red) and GBC (blue) models as in A ...
Helen T. Heinermann (8195529), Jutta Kretzberg (485830), Go Ashida (717470)   +2 more
core   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

An M-estimator of multivariate tail dependence.

AN M-ESTIMATOR OF TAIL DEPENDENCE. Extreme value theory is the part of probability and statistics that provides the theoretical background for modeling events that almost never happen.
Krajina, A.
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Clinical use of 3D computed tomography in diagnosis and therapy of tail necrosis in a ball python (Python regius)

Bulgarian Journal of Veterinary Medicine
The main musculoskeletal diseases in reptiles diagnosed through computed tomography (CT) are vertebral malformations and disorders. This diagnostic imaging technique is crucial for the outcome and prognosis of applied treatment.
Ts. Chaprazov
doaj   +1 more source

Tail Behaviour of the Euro [PDF]

, 2004
This paper empirically analyses risk in the Euro relative to other currencies. Comparisons are made between a sub period encompassing the final transitional stage to full monetary union with a sub period prior to this.
Cotter, John
core  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source