A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Simulation of tail boom vibrations using main rotor-fuselage Computational Fluid Dynamics (CFD) [PDF]
, 2017 In this work, fully-resolved rotor-fuselage interactional aerodynamics is used as the forcing term in a model based on the Euler-Bernoulli equation, aiming to simulate helicopter tail-boom vibration.
Barakos, George N. +4 more
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Structural Studies of the Phage G Tail Demonstrate an Atypical Tail Contraction
Viruses, 2021 Phage G is recognized as having a remarkably large genome and capsid size among isolated, propagated phages. Negative stain electron microscopy of the host–phage G interaction reveals tail sheaths that are contracted towards the distal tip and decoupled ...
Brenda González +7 more
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
EFFECT OF SOME FACTORS ON HEAD AND TAIL MEASUREMENTS OF MALYA BREED LAMBS
Животновъдни науки, 2014 This study was carried out to determine effects of some factors (birth weight, birth type, sex of lamb and maternal age) on head and tail measurements of Malya lambs (11/16 Akkaraman x 5/16 Deutsches Merinofleischschaf) reared at Malya state farm in ...
SÜLEYMAN ÇİLEK +1 more
doaj
On Weak Tail Domination of Random Vectors
, 2007 Motivated by a question of Krzysztof Oleszkiewicz we study a notion of weak tail domination of random vectors. We show that if the dominating random variable is sufficiently regular weak tail domination implies strong tail domination.
Latała, Rafał
core +1 more source
Gravitational-wave tails of tails [PDF]
Classical and Quantum Gravity, 1998 Contains 2 files: a tex file B98tailgrqc.tex and a latex file tabtail.tex. This version includes the correction of an Erratum to appear in Classical and Quantum Gravity (2005)
openaire +2 more sources
Study on Compressive Properties and Dynamic Characteristics of Polypropylene-Fiber-and-Cement-Modified Iron-Ore Tailing under Traffic Load [PDF]
, 2022 Ping Jiang +5 more
openalex +1 more source