Results 111 to 120 of about 113,227 (308)

Research situation of the disaster-causing mechanism of tailing dams and its developing trend

open access: yes工程科学学报, 2016
The disaster-causing mechanism of unstable tailing dams is extremely complex. However, the impact of multi-scale and multi-factor mechanical properties of railings is not adequately considered in existing studies on the disaster prevention of tailing ...
LI Zhang-hong, BU Lei, CHEN Long-gen
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Bristle-Tails and Spring-Tails

open access: yesThe American Naturalist, 1871
Mode of access: Internet.
openaire   +2 more sources

High precision half-life measurement of $^{147}$Sm $\alpha$ decay from thin-film sources

open access: yes, 2017
An investigation of the {\alpha}-decay of $^{147}$Sm was performed using an ultra low-background Twin Frisch-Grid Ionisation Chamber (TF-GIC). Four natural samarium samples were produced using pulsed laser deposition in ultra high vacuum.
Degering, Detlev   +4 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

A first approach to the characterization of water and sediments during the restoration of coal waste dumps in El Bierzo (NW Iberia)

open access: yesGeogaceta
Coal mining has been related to the problems of acid mine drainage (AMD) or acid rock drainage (ARD), causing high acidity and contamination by metals. Coal mining in El Bierzo coal basin, NW Iberian Peninsula, has resulted in several abandoned tailings
Sara Alcalde Aparicio   +6 more
doaj   +1 more source

A comparison between e-government practices in Taiwan and New Zealand. [PDF]

open access: yes, 2007
Few studies have focused on comparing the state of e-government in Western- and Non-Western settings, where the political, social, economic, and cultural environments can be markedly different.
Chen, Wan Jung   +2 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

The use of Pistia stratiotes compost as an ameliorant for chili growth and yields in the reclamation fresh tailing area of Timika, Papua

open access: yesJournal of Degraded and Mining Lands Management
Tailing land reclamation aims to improve the environment so that the tailing areas become productive for crop cultivation. The research was carried out in the tailings area of Mile 21.5 Timika from March to September 2022. The research aimed to study the
Saraswati Prabawardani   +5 more
doaj   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

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