Results 141 to 150 of about 29,738 (318)
Seismic Safety of Upstream Tailings Dams : A Risk-Informed Case
Emerging global standards such as the GISTM (Global Industry Standard on Tailings Management) center around risk management practices to protect people and the environment. However, many questions remain on how to address zero risk, how to quantify risk,
Li, Yuan +2 more
core
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
The Quillayes sand tailings dam in Chile design and operation
The Quillayes sand tailings dam of Los Pelambres mine, a company owned by Antofagasta Minerals, is currently the highest sand tailings dam in Chile. The dam reached its final height of 198m in 2008 after 10 years of construction and operation.
Campaña, Jose +3 more
core
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Oil sands tailings management projects : low return, business critical
In 2014, Independent Project Analysis (IPA) led Alberta’s first industry research study on the performance of oil sands tailings management capital projects. Although the industry has organized extensively to investigate and share technology strategies
Nicolaisen, Jennifer
core
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Breakage and reformation of flocs in oil sands tailings slurries
Tailings management presents a key challenge in effectively exploiting oil sands resources, since every barrel of bitumen recovered generates two to three barrels of tailings waste.
Watson, Philip +5 more
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Effect of terahertz irradiation on DNA damage repair in living cells
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source
Filter-pressed tailings facility design, construction, and operating guidelines
Filter-pressed tailings facilities have been designed, constructed, and operated since the late 1980 when Greens Creek, Alaska first adopted the method. Currently more and more mining companies are considering filter-pressed tailings management as a way ...
Caldwell, Jack, Crystal, Colleen
core
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source

