Results 101 to 110 of about 8,329 (233)

Improvement of β‐Xylosidase and Endoxylanase Activities in Talaromyces amestolkiae by Genetic Manipulation of the Transcriptional Activator XlnR

Microbial Biotechnology, Volume 18, Issue 5, May 2025.
A successful transformation procedure for the genetic manipulation of the fungus Talaromyces amestolkiae was developed, enabling the forced expression of the transcriptional activator XlnR. A mutant version of XlnR carrying a Val785Phe substitution led to remarkably higher β‐xylosidase and endoxylanase activities compared to the wild‐type strain, which
Ana Pozo‐Rodríguez, Miguel Ángel Peñalva, Jorge Barriuso, Eduardo A. Espeso, María Jesús Martínez   +4 more
wiley   +1 more source

Talaromyces marneffei Infection: Virulence Factors and Rapid Diagnostics

, 2022
Talaromyces (Penicillium) marneffei is a thermally dimorphic fungus that causes talaromycosis, and the pathogen is found throughout tropical and subtropical Asia. T. marneffei has specifically emerged as an opportunistic fungal pathogen in individuals with advanced HIV disease and, to a lesser extent, other immunocompromised conditions, but more ...
openaire   +2 more sources

Clinical Characteristics, Course, and Long-Term Outcomes in Patients with Talaromyces marneffei Infection: A 10-Year Retrospective Cohort Study

Infectious Disease and Therapy, 2023
Talaromyces marneffei (T. marneffei), a dimorphic fungus, causes local or disseminated infection in humans. We aimed to analyze the clinical characteristics, prognostic factors, and survival outcomes of patients with T.
Qingliang Yu, Meifang Wei, Rong Xiao, Xiao-min Liang, Siqiao Liang, Nan Ma, Siyao Wu, Y. Ning, Jingmin Deng, Mei-ling Yang, QUAN-FANG Chen, W. Zeng, Mei-hua Li, Xiaokai Feng, Zhiyi He   +14 more
semanticscholar   +1 more source

Hyper IgE Syndromes: Understanding, Management, and Future Perspectives: A Narrative Review

Health Science Reports, Volume 8, Issue 3, March 2025.
ABSTRACT Background and Aim Hyper IgE syndromes (HIES) are rare primary immunodeficiency characterized by susceptibility to specific infections, eczema, and elevated IgE levels. Pathogenic mutations in STAT3, IL6R, IL6ST, ERBB2IP, PGM3, ZNF431, SPINK5, TGFBR1/2, and CARD11 have been identified as genetic factors contributing to phenotypes of HIES lead ...
Mohammad Salehi, Zeinab Neshati, Hamid Ahanchian, Rana Tafrishi, Alireza Pasdar, Mojtaba Safi, Ehsan Ghayoor Karimiani   +6 more
wiley   +1 more source

Lung infection in an Indonesian papillary thyroid carcinoma patient

SAGE Open Medical Case Reports, 2017
Talaromycosis, a disseminated and progressive infection caused by Talaromyces marneffei , is highly endemic in the tropical region of Asia. However, accumulated data show very low incidence in Indonesia.
Surya Darma, Yusrizal Djam’an Saleh, Tri Wibawa   +2 more
doaj   +1 more source

A Machine Learning Model for Diagnosing Opportunistic Infections in HIV Patients: Broad Applicability Across Infection Types

Journal of Cellular and Molecular Medicine, Volume 29, Issue 6, March 2025.
ABSTRACT Opportunistic infections (OIs) are the leading cause of hospitalisation and mortality among Human Immunodeficiency Virus‐infected (HIV‐infected) patients. The diverse pathogen types and intricate clinical manifestations associated present a formidable challenge to the timely diagnosis of these infections.
Hao Chen, Fanxuan Chen, Yijun Wang, Enna Cai, Wangzheng Pan, Yichen Li, Zefei Mo, Hao Lou, Chufan Ren, Chenyue Dai, Xingbo Shan, Hui Ye, Zhenwei Xu, Pu Dong, Han Zhou, Shuya Xu, Tianye Zhu, Mingzhi Su, Xingguo Miao, Xiaoqu Hu, Liang Hong, Yi Wang, Feifei Su   +22 more
wiley   +1 more source

The Presence of Secondary Evans Syndrome in AIDS Patients with Talaromyces marneffei Infection

Infection and Drug Resistance, 2021
Mengyan Wang, Zhongdong Zhang, Jun Yan, Jinchuan Shi, Shourong Liu, Hu Wan Department II of Infectious Diseases, Xixi Hospital of Hangzhou, Hangzhou Sixth People’s Hospital, Hangzhou, 310023, People’s Republic of ChinaCorrespondence: Hu Wan ...
Wang M, Zhang Z, Yan J, Shi J, Liu S, Wan H   +5 more
doaj  

Assessing the potential risk of human pathogen resistance to medical antifungal treatments arising from agricultural use of fungicides with the same mode of action

Plant Pathology, Volume 74, Issue 2, Page 578-594, February 2025.
A mechanistic basis is described for assessment of resistance risk to medical antifungal treatments from agricultural use of fungicides of the same mode of action. Abstract A mechanistic basis is described for assessment of resistance risk to medical antifungal treatments from agricultural use of fungicides of the same mode of action.
Neil Paveley, Frank van den Bosch, Michael Grimmer   +2 more
wiley   +1 more source

Integration of Transcriptomics and Proteomics to Elucidate Inhibitory Effect and Mechanism of Antifungalmycin B from Marine Streptomyces hiroshimensis in Treating Talaromyces marneffei

Marine Drugs
Talaromyces marneffei (TM) is an opportunistic pathogenic fungus that mainly infects immunocompromised patients. Currently, the global prevalence of talaromycosis caused by TM is increasing, leading to an increased demand for anti-TM drugs.
Qiqi Li, Zhou Wang, Cuiping Jiang, Jianglin Yin, Yonghong Liu, Xinjian Qu, Xiangxi Yi, Chenghai Gao   +7 more
semanticscholar   +1 more source

Comparison of film array pneumonia panel to routine diagnostic methods and its potential impact in an adult intensive care unit in Hong Kong and the potential role of emergency departments

Hong Kong Journal of Emergency Medicine, Volume 31, Issue 4, Page 159-164, August 2024.
Abstract Background Pneumonia is a leading diagnosis for patients requiring critical care. Prediction of the causal organisms has proved challenging, and antibiotic overuse is a burning issue. Objective This study aimed to compare the results of the BioFire FilmArray Pneumonia Panel (PN Panel) to standard diagnostic methods and evaluate its potential ...
Ping Wu, Kin Ho Steven Ling
wiley   +1 more source