Results 1 to 10 of about 58,932 (285)

Acute Q fever pneumonia diagnosed by metagenomic next-generation sequencing

Journal of Infection in Developing Countries
Introduction: Q fever, a zoonotic disease caused by Coxiella burnetii (C. burnetii), presents diagnostic challenges due to its clinical and radiological nonspecificity, which often mimics community-acquired pneumonia, coupled with the limitations of ...
Bin Liu, Peng Huang, Yanchao Liang, Shuangbo Liu, Fangwei Chen, Xiping Luo, Tengjuan Xu, Bo Xie   +7 more
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Metagenomic Next-Generation Sequencing versus Traditional Pathogen Detection in the Diagnosis of Peripheral Pulmonary Infectious Lesions

Infection and Drug Resistance, 2020
Jie Huang,1,2 Erlie Jiang,3 Donglin Yang,3 Jialin Wei,3 Mingfeng Zhao,4 Jing Feng,1 Jie Cao1 1Department of Respiratory and Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China; 2Graduate School ...
Huang J, Jiang E, Yang D, Wei J, Zhao M, Feng J, Cao J   +6 more
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Metagenomic next‐generation sequencing in the early diagnosis of leptospirosis infection presenting as acalculous cholecystitis and septic shock in a non‐epidemic area after typhoons: A case report

Clinical Case Reports
Key Clinical Message Leptospirosis is an important zoonosis worldwide. Due to nonspecific clinical manifestation and poor recognition in non‐epidemic area, there is often a delay in diagnosis and treatment.
Xueying Han, Bihan Huang, Lilei Yang, Jinglan Wu, Haigang Zhang   +4 more
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Unravelling the enigma of the human microbiome: Evolution and selection of sequencing technologies

Microbial Biotechnology
The human microbiome plays a crucial role in maintaining health, with advances in high‐throughput sequencing technology and reduced sequencing costs triggering a surge in microbiome research.
Xin Yi, Hong Lu, Xiang Liu, Junyi He, Bing Li, Zhelong Wang, Yujing Zhao, Xinri Zhang, Xiao Yu   +8 more
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Application of targeted metagenomic next-generation sequencing in pneumonia patients

Microbiology Spectrum
After the coronavirus disease 2019 (COVID-19) pandemic, the incidence rate of mixed infections, especially in critically ill patients with severe pneumonia, increases due to the immunity gap and has also been proven to be associated with mortality ...
Guanjun Ren, Liyun Ma, Chunliang Yan, Qishan Xue, Huijuan Zhang, Wei Wang, Xiyan Ren, Yun Lei, Shaofei Li, Yafeng Liu, Qingyue Zheng, Shigang Wei, Yue Zhang, Xiao Wang   +13 more
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Comparing the diagnostic value of targeted with metagenomic next-generation sequencing in immunocompromised patients with lower respiratory tract infection

Annals of Clinical Microbiology and Antimicrobials
Background Accurate identification of the etiology of lower respiratory tract infections (LRTI) is crucial, particularly for immunocompromised patients with more complex etiologies.
Muyun Wei, Shaowei Mao, Shuangshuang Li, Kangyi Gu, Dejian Gu, Shengjie Bai, Xinhua Lu, Min Li   +7 more
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Metagenomic Next-Generation Sequencing for Pulmonary Fungal Infection Diagnosis: Lung Biopsy versus Bronchoalveolar Lavage Fluid

Infection and Drug Resistance, 2021
Lei Yang,1 Junxiu Song,1 Yubao Wang,2 Jing Feng1 1Department of Respiratory and Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China; 2Institute of Infectious Diseases, The Second Hospital of Tianjin ...
Yang L, Song J, Wang Y, Feng J
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Diagnostic efficacy of metagenomic next-generation sequencing for spinal infections

陆军军医大学学报
Objective To comparatively evaluate the diagnostic value of metagenomic next-generation sequencing (mNGS) versus conventional microbial culture in spinal infections.
LIU Shuang, HE Jinyue, CHEN Hui
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Metagenomic Next-Generation Sequencing Unravels Talaromyces Marneffei-Induced Bone Destruction in an HIV-Negative Woman: A Case Report with Fatal Outcome

Infection and Drug Resistance
Jiayi Chen,* Zixiang Pang,* Chengyu Qin, Zuhai Huang, Yuanming Chen Department of Spinal Orthopedics, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People’s Republic of China*These authors ...
Chen J, Pang Z, Qin C, Huang Z, Chen Y
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Cryptococcus Neoformans Osteomyelitis of the Right Ankle Diagnosed by Metagenomic Next-Generation Sequencing in a HIV-Negative Patient with Tuberculous Lymphadenitis and Pulmonary Tuberculosis: A Case Report and Recent Literature Review

Infection and Drug Resistance
Yao Qin,1 Xingwu Zou,1 Yanghui Jin,2 Jinmeng Li,3 Qingshan Cai1 1Department of Tuberculosis, Hangzhou Red Cross Hospital, Hangzhou, People’s Republic of China; 2Department of Orthopaedic, Hangzhou Red Cross Hospital, Hangzhou, People’s Republic of China;
Qin Y, Zou X, Jin Y, Li J, Cai Q
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