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Metagenomic next-generation sequencing: new horizons in microbiology [PDF]
Frontiers in Cellular and Infection MicrobiologyThe COVID-19 pandemic has exposed vulnerabilities in global health systems while accelerating the adoption of metagenomic next-generation sequencing (mNGS) as a transformative tool for culture-independent, unbiased microbial detection.
Nan Guo +8 more
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Leishmaniasis Diagnosis via Metagenomic Next-Generation Sequencing [PDF]
Frontiers in Cellular and Infection Microbiology, 2020 Leishmaniasis is a vector-borne disease caused by Leishmania. Although the incidence of leishmaniasis in China is currently low, it has not been completely eradicated.
Hongbin Chen +6 more
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Application of metagenomic next-generation sequencing in cutaneous tuberculosis
Frontiers in Cellular and Infection Microbiology, 2022 Tuberculous infection in a skin wound is a rare but well-known condition. This study describes a child infected with tuberculosis after being wounded. Because of swelling and pain in his wrist tissue, he was admitted to the Affiliated Hospital of Jining ...
Min Kong +7 more
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Computed tomography–guided precision biopsy combined with metagenomic next-generation sequencing for etiological diagnosis in patients with blood culture-negative systemic infections [PDF]
Journal of International Medical ResearchObjective To evaluate the diagnostic efficacy of computed tomography–guided percutaneous biopsy combined with metagenomic next-generation sequencing in patients with blood culture-negative systemic infections and to assess the clinical impact of using ...
Yongkun Fang +4 more
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Metagenomic Next-Generation Sequencing Enhances Pathogen Detection and Prognostic Stratification in Hematopoietic Stem Cell Transplantation Recipients [PDF]
Infection and Drug ResistanceYing Liu, Xintong Bian, Hongxu Wang, Dijiao TangDepartment of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China*These authors contributed equally to this ...
Liu Y, Bian X, Wang H, Tang D
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Infection and Drug Resistance, 2020 Jie Huang,1,2 Erlie Jiang,3 Donglin Yang,3 Jialin Wei,3 Mingfeng Zhao,4 Jing Feng,1 Jie Cao1 1Department of Respiratory and Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China; 2Graduate School ...
Huang J +6 more
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Scientific Reports, 2023 This study assessed the application of metagenomic next-generation sequencing in pathogen detection of periprosthetic joint infections. A total of 95 cases who previously had undergone hip and knee replacement undergoing revision from January 2018 to ...
Linjie Hao +7 more
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BMC Infectious Diseases, 2021 Background In this study, we aimed to perform a comprehensive analysis on the metagenomic next-generation sequencing for the etiological diagnosis of septic patients, and further to establish optimal read values for detecting common pathogens. Methods In
Di Ren +18 more
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Improving Pulmonary Infection Diagnosis with Metagenomic Next Generation Sequencing
Frontiers in Cellular and Infection Microbiology, 2021 Pulmonary infections are among the most common and important infectious diseases due to their high morbidity and mortality, especially in older and immunocompromised individuals.
Yi-Yi Qian +15 more
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Epileptic Seizure after Use of Moxifloxacin in Man with Legionella longbeachae Pneumonia
Emerging Infectious Diseases, 2020 Legionellosis caused by Legionella longbeachae is diagnosed mainly by PCR. We report a case of L. longbeachae infection in mainland China, which was diagnosed by metagenomic next-generation sequencing, in a man who developed an epileptic seizure after ...
Jin-Yong Wang +3 more
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