Results 11 to 20 of about 30,985 (257)
BMC Infectious Diseases, 2021 Background In this study, we aimed to perform a comprehensive analysis on the metagenomic next-generation sequencing for the etiological diagnosis of septic patients, and further to establish optimal read values for detecting common pathogens. Methods In
Di Ren +18 more
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Improving Pulmonary Infection Diagnosis with Metagenomic Next Generation Sequencing
Frontiers in Cellular and Infection Microbiology, 2021 Pulmonary infections are among the most common and important infectious diseases due to their high morbidity and mortality, especially in older and immunocompromised individuals.
Yi-Yi Qian +15 more
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Frontiers in Cellular and Infection Microbiology, 2022 IntroductionRapid, sensitive, and specific laboratory assays are critical for the diagnosis and management of central nervous system (CNS) infections. The purpose of this study is to explore the intellectual landscape of research investigating methods ...
Yangyang Guo +6 more
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Epileptic Seizure after Use of Moxifloxacin in Man with Legionella longbeachae Pneumonia
Emerging Infectious Diseases, 2020 Legionellosis caused by Legionella longbeachae is diagnosed mainly by PCR. We report a case of L. longbeachae infection in mainland China, which was diagnosed by metagenomic next-generation sequencing, in a man who developed an epileptic seizure after ...
Jin-Yong Wang +3 more
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Frontiers in Medicine, 2022 BackgroundAnaerobic meningitis is a severe central nervous system infection associated with significant neurological sequelae and high mortality. However, the precise detection of causative pathogen(s) remains difficult because anaerobic bacteria are ...
Xiaoqiang Li +4 more
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Emergomyces orientalis Emergomycosis Diagnosed by Metagenomic Next-Generation Sequencing
Emerging Infectious Diseases, 2021 Emergomyces is a newly described dimorphic fungus genus; it may cause fatal infections in immunocompromised patients, but diagnosis is often delayed. We report a case of disseminated emergomycosis caused by the novel species Emergomyces orientalis in a ...
Da He +9 more
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Pneumocystis Jirovecii Pneumonia Diagnosis via Metagenomic Next-Generation Sequencing
Frontiers in Medicine, 2022 The incidence of non-HIV-infected Pneumocystis Jirovecii Pneumonia (PJP) is increasing. The prognosis for non-HIV PJP is poor and diagnostic tests are of lower sensitivity in non-HIV patients.
Xiaoxiao Lu +6 more
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Metagenomic Next-Generation Sequencing for Periprosthetic Joint Infections
Cureus, 2023 Periprosthetic joint infection (PJI) after arthroplasty is a major complication, which requires significant resources, resulting in high costs for the medical system. In recent years, significant progress has been made in the diagnosis and treatment of periprosthetic infections, the identification of the pathogen being the central element in the ...
Cretu, Bogdan +6 more
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NeSSM: A Next-Generation Sequencing Simulator for Metagenomics
PLoS ONE, 2013 Metagenomics can reveal the vast majority of microbes that have been missed by traditional cultivation-based methods. Due to its extremely wide range of application areas, fast metagenome sequencing simulation systems with high fidelity are in great demand to facilitate the development and comparison of metagenomics analysis tools.We present here a ...
Ben Jia +5 more
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BMC Infectious Diseases, 2020 Background The aims of this study were to (1) evaluate the efficacy and safety of targeted antibiotics for the treatment of culture-negative prosthetic joint infection based on metagenomic next-generation sequencing results and (2) verify the accuracy ...
Chaoxin Wang +4 more
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