Results 11 to 20 of about 6,252 (250)

Clinical application of metagenomic next-generation sequencing in tuberculosis diagnosis

Frontiers in Cellular and Infection Microbiology, 2023
ObjectiveThe purpose of this study was to evaluate the clinical diagnostic value of metagenomic next-generation sequencing (mNGS) for tuberculosis (TB).MethodsThis retrospective study included 52 patients with suspected TB infection.
Ying Liu, Ying Liu, Huifen Wang, Huifen Wang, Yaoguang Li, Yaoguang Li, Zujiang Yu, Zujiang Yu   +7 more
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Clinical applications and challenges of metagenomic next-generation sequencing in the diagnosis of pediatric infectious disease

Journal of Laboratory Medicine
Infectious diseases seriously threaten the lives of children. Timely and accurate detection of pathogenic microorganisms and targeted medication are the keys to the diagnosing and treatment of infectious diseases in children.
Guo Qiang, Zhang Shihai
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Metagenomic Next-Generation Sequencing Reveals Porphyromonas gingivalis in Geriatric Severe Pneumonia Complicated by Empyema: Case Report

Infection and Drug Resistance
Na Guo,1,* Guannan Ma,2,* Huimin Liu,1 Jingxuan Qiu,1 Yan Yu,1 Yunlei Gao,1 Zhong Yi,1 Zhirong Wan,1 Lei Zhang,2,3 Xiaorui Wu4 1Department of Geriatrics, Aerospace Center Hospital, Beijing, People’s Republic of China; 2Medical Research ...
Guo N, Ma G, Liu H, Qiu J, Yu Y, Gao Y, Yi Z, Wan Z, Zhang L, Wu X   +9 more
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Metagenomic Next-Generation Sequencing Unveils Prognostic Microbial Synergism and Guides Precision Therapy in Candidemia: A Retrospective Cohort Study

Infection and Drug Resistance
Yuhui Chen,1,2 Meng Li,1,2 Xinai Gan,1,2 Yutong Wang,1,2 Xinzhu Tang,1,2 Yongzhao Zhou,3,4 Ting Niu1,5,6 1Department of Hematology, Institute of Hematology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 2West China School ...
Chen Y, Li M, Gan X, Wang Y, Tang X, Zhou Y, Niu T   +6 more
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Metagenomic Next-Generation Sequencing Reveals Tannerella forsythia in Lung Abscesses: A Retrospective Case Series Linking Smoking, Oral Health, and Diagnostic Challenges

Infection and Drug Resistance
Wen Wang, Qiongya Mo, Xuchun Ding,* Junjie Pan* Department of Respiratory and Critical Care Medicine, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, People’s Republic of China*
Wang W, Mo Q, Ding X, Pan J
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Application of targeted metagenomic next-generation sequencing in pneumonia patients

Microbiology Spectrum
After the coronavirus disease 2019 (COVID-19) pandemic, the incidence rate of mixed infections, especially in critically ill patients with severe pneumonia, increases due to the immunity gap and has also been proven to be associated with mortality ...
Guanjun Ren, Liyun Ma, Chunliang Yan, Qishan Xue, Huijuan Zhang, Wei Wang, Xiyan Ren, Yun Lei, Shaofei Li, Yafeng Liu, Qingyue Zheng, Shigang Wei, Yue Zhang, Xiao Wang   +13 more
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Direct detection and identification of periprosthetic joint infection pathogens by metagenomic next-generation sequencing

Scientific Reports, 2023
This study assessed the application of metagenomic next-generation sequencing in pathogen detection of periprosthetic joint infections. A total of 95 cases who previously had undergone hip and knee replacement undergoing revision from January 2018 to ...
Linjie Hao, Pengfei Wen, Wei Song, Binfei Zhang, Yanjie Wu, Yumin Zhang, Tao Ma, Yusheng Qiu   +7 more
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The microbiological diagnostic performance of metagenomic next-generation sequencing in patients with sepsis

BMC Infectious Diseases, 2021
Background In this study, we aimed to perform a comprehensive analysis on the metagenomic next-generation sequencing for the etiological diagnosis of septic patients, and further to establish optimal read values for detecting common pathogens. Methods In
Di Ren, Chao Ren, Renqi Yao, Lin Zhang, Xiaomin Liang, Guiyun Li, Jiaze Wang, Xinke Meng, Jia Liu, Yu Ye, Haoli Li, Sha Wen, Yanhong Chen, Dan Zhou, Xisi He, Xiaohong Li, Kai Lai, Ying Li, Shuiqing Gui   +18 more
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Improving Pulmonary Infection Diagnosis with Metagenomic Next Generation Sequencing

Frontiers in Cellular and Infection Microbiology, 2021
Pulmonary infections are among the most common and important infectious diseases due to their high morbidity and mortality, especially in older and immunocompromised individuals.
Yi-Yi Qian, Hong-Yu Wang, Yang Zhou, Hao-Cheng Zhang, Yi-Min Zhu, Xian Zhou, Yue Ying, Peng Cui, Hong-Long Wu, Hong-Long Wu, Wen-Hong Zhang, Wen-Hong Zhang, Wen-Hong Zhang, Wen-Hong Zhang, Jia-Lin Jin, Jing-Wen Ai   +15 more
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Trends and Developments in the Detection of Pathogens in Central Nervous System Infections: A Bibliometric Study

Frontiers in Cellular and Infection Microbiology, 2022
IntroductionRapid, sensitive, and specific laboratory assays are critical for the diagnosis and management of central nervous system (CNS) infections. The purpose of this study is to explore the intellectual landscape of research investigating methods ...
Yangyang Guo, Yanlin Yang, Ming Xu, Guangzhi Shi, Jianxin Zhou, Jindong Zhang, Hongliang Li   +6 more
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