Results 11 to 20 of about 4,937,404 (296)

Application of metagenomic next-generation sequencing and targeted metagenomic next-generation sequencing in diagnosing pulmonary infections in immunocompetent and immunocompromised patients

Frontiers in Cellular and Infection Microbiology
BackgroundMetagenomic next-generation sequencing (mNGS) technology has been widely used to diagnose various infections. Based on the most common pathogen profiles, targeted mNGS (tNGS) using multiplex PCR has been developed to detect pathogens with ...
Yong Liu, Wencai Wu, Yunping Xiao, Hongyan Zou, Sijia Hao, Yanfang Jiang   +5 more
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Metagenomic next-generation sequencing targeted and metagenomic next-generation sequencing for pulmonary infection in HIV-infected and non-HIV-infected individuals

Frontiers in Cellular and Infection Microbiology
BackgroundWhen individuals infected with human immunodeficiency virus (HIV) experience pulmonary infections, they often exhibit severe symptoms and face a grim prognosis.
Luyao Sun, Kaiyu Zhang, Yong Liu, Lihe Che, Peng Zhang, Bin Wang, Na Du   +6 more
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Clinical applications and challenges of metagenomic next-generation sequencing in the diagnosis of pediatric infectious disease

Journal of Laboratory Medicine
Infectious diseases seriously threaten the lives of children. Timely and accurate detection of pathogenic microorganisms and targeted medication are the keys to the diagnosing and treatment of infectious diseases in children.
Guo Qiang, Zhang Shihai
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Application of Metagenomic Next-Generation Sequencing in Mycobacterium tuberculosis Infection

Frontiers in Medicine, 2022
The fight against Mycobacterium tuberculosis (MTB) has been going on for thousands of years, while it still poses a threat to human health. In addition to routine detections, metagenomic next-generation sequencing (mNGS) has begun to show presence as a ...
Yaoguang Li, Yaoguang Li, Mengfan Jiao, Mengfan Jiao, Ying Liu, Ying Liu, Zhigang Ren, Ang Li   +7 more
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Pathogenic Detection by Metagenomic Next-Generation Sequencing in Osteoarticular Infections [PDF]

Frontiers in Cellular and Infection Microbiology, 2020
Objectives: To evaluate metagenomic next-generation sequencing (mNGS) as a diagnostic tool in detecting pathogens from osteoarticular infection (OAI) samples.Methods: 130 samples of joint fluid, sonicate fluid, and tissue were prospectively collected ...
Zi-da Huang, Zi-jie Zhang, Bin Yang, Wen-bo Li, Chong-jing Zhang, Xin-yu Fang, Chao-fan Zhang, Wen-ming Zhang, Jian-hua Lin   +8 more
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Metagenomic Next-Generation Sequencing Reveals Porphyromonas gingivalis in Geriatric Severe Pneumonia Complicated by Empyema: Case Report [PDF]

Infection and Drug Resistance
Na Guo,1,* Guannan Ma,2,* Huimin Liu,1 Jingxuan Qiu,1 Yan Yu,1 Yunlei Gao,1 Zhong Yi,1 Zhirong Wan,1 Lei Zhang,2,3 Xiaorui Wu4 1Department of Geriatrics, Aerospace Center Hospital, Beijing, People’s Republic of China; 2Medical Research ...
Guo N, Ma G, Liu H, Qiu J, Yu Y, Gao Y, Yi Z, Wan Z, Zhang L, Wu X   +9 more
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Clinical application of metagenomic next-generation sequencing in tuberculosis diagnosis

Frontiers in Cellular and Infection Microbiology, 2023
ObjectiveThe purpose of this study was to evaluate the clinical diagnostic value of metagenomic next-generation sequencing (mNGS) for tuberculosis (TB).MethodsThis retrospective study included 52 patients with suspected TB infection.
Ying Liu, Ying Liu, Huifen Wang, Huifen Wang, Yaoguang Li, Yaoguang Li, Zujiang Yu, Zujiang Yu   +7 more
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Metagenomic Next-Generation Sequencing Unveils Prognostic Microbial Synergism and Guides Precision Therapy in Candidemia: A Retrospective Cohort Study [PDF]

Infection and Drug Resistance
Yuhui Chen,1,2 Meng Li,1,2 Xinai Gan,1,2 Yutong Wang,1,2 Xinzhu Tang,1,2 Yongzhao Zhou,3,4 Ting Niu1,5,6 1Department of Hematology, Institute of Hematology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 2West China School ...
Chen Y, Li M, Gan X, Wang Y, Tang X, Zhou Y, Niu T   +6 more
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Metagenomic Next-Generation Sequencing Reveals Tannerella forsythia in Lung Abscesses: A Retrospective Case Series Linking Smoking, Oral Health, and Diagnostic Challenges [PDF]

Infection and Drug Resistance
Wen Wang, Qiongya Mo, Xuchun Ding,* Junjie Pan* Department of Respiratory and Critical Care Medicine, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, People’s Republic of China*
Wang W, Mo Q, Ding X, Pan J
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Trends and Developments in the Detection of Pathogens in Central Nervous System Infections: A Bibliometric Study

Frontiers in Cellular and Infection Microbiology, 2022
IntroductionRapid, sensitive, and specific laboratory assays are critical for the diagnosis and management of central nervous system (CNS) infections. The purpose of this study is to explore the intellectual landscape of research investigating methods ...
Yangyang Guo, Yanlin Yang, Ming Xu, Guangzhi Shi, Jianxin Zhou, Jindong Zhang, Hongliang Li   +6 more
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