Results 41 to 50 of about 58,932 (285)

Meeting report : 1st international functional metagenomics workshop May 7–8, 2012, St. Jacobs, Ontario, Canada [PDF]

, 2012
This report summarizes the events of the 1st International Functional Metagenomics Workshop. The workshop was held on May 7 and 8 in St. Jacobs, Ontario, Canada and was focused on building a core international functional metagenomics community, exploring
Ashby, Deborah, Brady, Sean F., Charles, Trevor, Cowan, Don A., Doemer, John, Edwards, E. A., Engel, Katja, Fiebig, Klaus, Liles, Mark R., Martens, Eric C., McCormac, Dennis, Mead, David A., Miyazaki, Kentaro, Moreno-Hagelsieb, Gabriel, Neufeld, Josh D., O’Gara, F., Reid, A., Rose, David R., Sessitsch, Angela, Simonet, Pascal, Sjöling, Sara, Smalla, K., Streit, Wolfgang R., Tedman-Jones, Jennifer, Valla, Svein, Wellington, E. M. H., Wu, Cheng-Cang   +26 more
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Comparison and development of a metagenomic next-generation sequencing protocol for combined detection of DNA and RNA pathogens in cerebrospinal fluid

BMC Infectious Diseases, 2022
Background The purpose of this study was to evaluate different pretreatment, extraction, amplification, and library generation methods for metagenomic next-generation sequencing (mNGS) of cerebrospinal fluid (CSF) and to develop an efficient procedure ...
Hanfang Jiang, Zhihao Xing, Xiaorong Liu, Qiang Chai, Zefeng Xin, Chunqing Zhu, Ruihong Lin, Xuwen Deng, Dong Cui, HongDan Gao, Dongli Ma   +10 more
doaj   +1 more source

The impact of sequence database choice on metaproteomic results in gut microbiota studies [PDF]

, 2016
Background: Elucidating the role of gut microbiota in physiological and pathological processes has recently emerged as a key research aim in life sciences.
Addis, Maria Filippa, Deligios, Massimo, Fraumene, Cristina, Manghina, Valeria, Martens, Lennart, Muth, Thilo, Pagnozzi, Daniela, Palomba, Antonio, Rapp, Erdmann, Tanca, Alessandro, Uzzau, Sergio   +10 more
core   +4 more sources

Preliminary assessment of nanopore-based metagenomic sequencing for the diagnosis of prosthetic joint infection

International Journal of Infectious Diseases, 2020
Objectives: Pathogen identification is crucial for the diagnosis and management of periprosthetic joint infection (PJI). Although culturing methods are the foundation of pathogen detection in PJI, false-negative results often occur.
Chao-xin Wang, Zida Huang, Wei Fang, Zijie Zhang, Xinyu Fang, Wenbo Li, Bin Yang, Luyao Chen, Xiangzhi Liang, Huan Hu, Duozhi Shi, Shela Lee, Wenming Zhang   +12 more
doaj   +1 more source

NeSSM: A Next-Generation Sequencing Simulator for Metagenomics

PLoS ONE, 2013
Metagenomics can reveal the vast majority of microbes that have been missed by traditional cultivation-based methods. Due to its extremely wide range of application areas, fast metagenome sequencing simulation systems with high fidelity are in great demand to facilitate the development and comparison of metagenomics analysis tools.We present here a ...
Ben Jia, Liming Xuan, Kaiye Cai, Zhiqiang Hu, Liangxiao Ma, Chaochun Wei   +5 more
openaire   +4 more sources

Metagenomic Next-Generation Sequencing for Diagnostically Challenging Mucormycosis in Patients with Hematological Malignancies

Infection and Drug Resistance, 2022
Meng Zhang,1,* Wenyi Lu,2,* Danni Xie,1 Jiaxi Wang,1 Xia Xiao,2 Yedi Pu,2 Juanxia Meng,2 Hairong Lyu,2 Mingfeng Zhao2 1First Center Clinic College of Tianjin Medical University, Tianjin, 300192, People’s Republic of China; 2Department of ...
Zhang M, Lu W, Xie D, Wang J, Xiao X, Pu Y, Meng J, Lyu H, Zhao M   +8 more
doaj  

Metagenomic Next-generation Sequencing: Application in Infectious Diseases

Exploratory Research and Hypothesis in Medicine, 2021
Infectious diseases have always been a difficult clinical problem, especially severe infections and those infections of unknown origin. The invention of a new detection method is particularly important and urgent. Metagenomic next-generation sequencing (mNGS) is a high-throughput sequencing method that sequences microbial DNA and RNAs from fluid or ...
Yan Li, Qiao Yang, Jianqiang Ding
openaire   +1 more source

Unbiased taxonomic annotation of metagenomic samples [PDF]

, 2018
The classification of reads from a metagenomic sample using a reference taxonomy is usually based on first mapping the reads to the reference sequences and then classifying each read at a node under the lowest common ancestor of the candidate sequences ...
Bruno Fosso, Cormen T.H., Fosso B., Francesc Rosselló, Gabriel Valiente, Garey M.R., Graziano Pesole, Gurobi Optimization, Inc., Huson D., Jaccard P., Navas-Molina J.A., Powers D.M.W., Thomas T., Wooley J.C.   +13 more
core   +2 more sources

Multi-Omic Profiling of Melophlus Sponges Reveals Diverse Metabolomic and Microbiome Architectures that Are Non-overlapping with Ecological Neighbors. [PDF]

, 2020
Marine sponge holobionts, defined as filter-feeding sponge hosts together with their associated microbiomes, are prolific sources of natural products. The inventory of natural products that have been isolated from marine sponges is extensive. Here, using
Agarwal, Vinayak, Allen, Eric E, Biggs, Jason S, Garg, Neha, Mohanty, Ipsita, Podell, Sheila   +5 more
core   +2 more sources

Metagenomic sequencing unravels gene fragments with phylogenetic signatures of O2-tolerant NiFe membrane-bound hydrogenases in lacustrine sediment [PDF]

, 2015
Many promising hydrogen technologies utilising hydrogenase enzymes have been slowed by the fact that most hydrogenases are extremely sensitive to O2. Within the group 1 membrane-bound NiFe hydrogenase, naturally occurring tolerant enzymes do exist, and ...
Couto, Jillian M., Ijaz, Umer Zeeshan, Phoenix, Vernon R., Schirmer, Melanie, Sloan, William T.   +4 more
core   +1 more source