Results 31 to 40 of about 58,932 (285)
Metagenomic Next-Generation Sequencing for Periprosthetic Joint Infections
Cureus, 2023 Periprosthetic joint infection (PJI) after arthroplasty is a major complication, which requires significant resources, resulting in high costs for the medical system. In recent years, significant progress has been made in the diagnosis and treatment of periprosthetic infections, the identification of the pathogen being the central element in the ...
Cretu, Bogdan +6 more
openaire +2 more sources
MetAMOS: A modular and open source metagenomic assembly and analysis pipeline [PDF]
, 2013 © 2013 Treangen et al. We describe MetAMOS, an open source and modular metagenomic assembly and analysis pipeline. MetAMOS represents an important step towards fully automated metagenomic analysis, starting with next-generation sequencing reads and ...
Astrovskaya, I +8 more
core +5 more sources
Neurobrucellosis: Unexpected Answer From Metagenomic Next-Generation Sequencing [PDF]
Journal of the Pediatric Infectious Diseases Society, 2017 A diagnosis of brucellosis can be difficult because routine culture and serological methods exhibit variable sensitivity and specificity. We present the use of a metagenomic next- generation sequencing assay to diagnose a case of neurobrucellosis from cerebrospinal fluid, resulting in the institution of appropriate antibiotic treatment and a favorable ...
Mongkolrattanothai, Kanokporn +9 more
openaire +4 more sources
BMC Infectious Diseases, 2020 Background The aims of this study were to (1) evaluate the efficacy and safety of targeted antibiotics for the treatment of culture-negative prosthetic joint infection based on metagenomic next-generation sequencing results and (2) verify the accuracy ...
Chaoxin Wang +4 more
doaj +1 more source
Metagenomic next-generation sequencing to diagnose atypical severe scrub typhus
Journal of Microbiology, Immunology and Infection, 2022 Zuan Zhan +4 more
doaj +3 more sources
Metagenomic-based Surveillance of Pacific Coast tick Dermacentor occidentalis Identifies Two Novel Bunyaviruses and an Emerging Human Ricksettsial Pathogen. [PDF]
, 2017 An increasing number of emerging tick-borne diseases has been reported in the United States since the 1970s. Using metagenomic next generation sequencing, we detected nucleic acid sequences from 2 novel viruses in the family Bunyaviridae and an emerging ...
Bouquet, Jerome +5 more
core +2 more sources
Xiehe Yixue Zazhi, 2023 Traditional microbial detection methods have difficulty meeting the needs of pathogen detection in the clinic. In recent years, metagenomic next-generation sequencing (mNGS) technology has emerged and been widely used in the diagnosis of various ...
DIAO Zhenli, LI Jinming
doaj +1 more source
An optimized methodology for whole genome sequencing of RNA respiratory viruses from nasopharyngeal aspirates [PDF]
, 2018 Over the last decade, the number of viral genome sequences deposited in available databases has grown exponentially. However, sequencing methodology vary widely and many published works have relied on viral enrichment by viral culture or nucleic acid ...
Goya, Stephanie +9 more
core +2 more sources
Frontiers in Microbiology, 2020 Background: We conducted this retrospective study to reveal the accuracy of metagenomic next-generation sequencing (mNGS) for diagnosing osteoarticular infections from fresh abscess specimens obtained from patients in an HIV-naive population.Methods: We ...
Mingwei Zhao +7 more
doaj +1 more source
Unbiased Metagenomic Sequencing for Pediatric Meningitis in Bangladesh Reveals Neuroinvasive Chikungunya Virus Outbreak and Other Unrealized Pathogens. [PDF]
, 2019 The burden of meningitis in low-and-middle-income countries remains significant, but the infectious causes remain largely unknown, impeding institution of evidence-based treatment and prevention decisions.
Crawford, Emily D. +25 more
core +2 more sources