Results 191 to 200 of about 106,118 (266)

CCL26‐Mediated Modulation of Endothelial Secretome by Hypoxia‐Induced Tumor‐Derived Exosomes Enhances Metastatic Progression in Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Background Tumor cells adapt to hypoxia by releasing hiTDExs enriched with bioactive molecules that modulate endothelial behavior and promote tumor progression. This study aimed to characterize how hypoxia‐induced HNSCC exosomes reshape the endothelial secretome and contribute to metastatic potential.
Ozel Capik, Sevil Tekman, Betul Gundogdu, Ahsen Kilic, Rumeysa Polat, Omer Aydin, Omer Faruk Karatas   +6 more
wiley   +1 more source

Barriers to SGLT2 inhibitor prescribing in primary care: findings from a cross-sectional questionnaire study in England. [PDF]

Clin Kidney J
Dattani R, Purssell N, Desilva R, Joshi M, Frankel AH, Ashrafian H, Darzi A, Tam FWK.   +7 more
europepmc   +1 more source

Integrating Immunotherapy Into Head and Neck Surgery: Bridging Tumor Biology to Perioperative Decision‐Making, a Review

Head &Neck, EarlyView.
ABSTRACT Objective To provide a comprehensive review of the biological rationale, clinical evidence, and practical perioperative management of immunotherapy for the head and neck surgeon. Summary Background Data Standard treatment for resectable head and neck squamous cell carcinoma (HNSCC) has reached a survival plateau, with over 50% of patients ...
Nicholas Brian Shannon, Bruce Ashford
wiley   +1 more source

TCF12-mediated transcriptional activation of CCDC34 is involved in the positive feedback of tumor-associated macrophages and EMT to promote LUSC. [PDF]

Cell Biol Toxicol
Yu J, Zhan Q.
europepmc   +1 more source

Perceived benefits and constraints of artificial intelligence integration in teachers' college libraries: a TAM-based study. [PDF]

Front Artif Intell
Chibidi I, Magwa L.
europepmc   +1 more source

Refined Jianpi Huayu Jiedu Decoction Attenuates TAM-Induced Spasmolytic Polypeptide-Expressing Metaplasia (SPEM) by Modulating LCN2-Associated Mitochondrial Dysfunction. [PDF]

Pharmaceuticals (Basel)
Fang C, Zhang S, He P, Lai Y, Luo R, Zhang Y, Liu S, Xie Z, Pan H, Liu W.   +9 more
europepmc   +1 more source

Integrin CD11b/CD18 reprograms macrophage polarization by suppressing ERK/STAT3 signaling to enhance antitumor immunity in colitis-associated colorectal cancer. [PDF]

J Immunother Cancer
Lin Y, Liu YK, Mi P, Zhao XL, Lin JH, Cheng XS, Liang LY, Huang YD, Huo YN, Xie GJ, Ye ZY, Guleng B.   +11 more
europepmc   +1 more source

Lung Cancer Patients Display Increased Expression of Bovine Meat and Milk Factor (BMMF) Proteins in Peritumor Alveolar Macrophages

International Journal of Cancer, EarlyView.
Plasmid‐like DNA sequences frequently found in bovine milk and serum have been proposed as infectious agents promoting indirect carcinogenesis. This multi‐omics study detected immune cells positive for these bovine meat and milk factors (BMMFs) in patients with lung cancer, with BMMF expression inversely correlated with smoking intensity.
Nives Cecere, Kristina Alikhanyan, Claudia Ernst, Lisa Häfele, Lars Feuerbach, Imke Grewe, Sumen Siqin, Karin Gunst, Gunjan Shukla, Veronika Frehtman, Claudia Tessmer, Florian Eichhorn, Michael Allgäuer, Alexander Brobeil, Ilse Hofmann, Barbara Leuchs, Marc A. Schneider, Timo Bund   +17 more
wiley   +1 more source

Breast Cancer Milieu Maneuvers Cancer-Associated Macrophages to Synergize Neoplastic Repertoires. [PDF]

Cancers (Basel)
Lin HJ, Liu Y, Langevin B, Lin J.
europepmc   +1 more source