Results 61 to 70 of about 293,472 (265)
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Processing system and algorithms for the TanDEM-X mission [PDF]
In 2009, the German radar satellite TerraSAR-X will be supplemented with the TanDEM-X satellite to form the first bi-static single pass interferometer in space. TanDEM-X will fly close to TerraSAR-X in a controlled helix configuration for 3 years to jointly acquire interferometric SAR data in bistatic mode.
Breit, Helko +7 more
openaire +2 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Results of the TanDEM-X Baseline Calibration
The TanDEM-X mission based on two satellites provides a radar interferometer in space with the goal to derive a global Digital Elevation Model (DEM) with never achieved quality for a global coverage: a global DEM with a relative height accuracy of 2 m and 10 m absolute.
Walter Antony, John Mohan +5 more
openaire +2 more sources
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Iceberg topography and volume classification using TanDEM-X interferometry [PDF]
Icebergs in polar regions affect water salinity, alter marine habitats, and impose serious hazards on maritime operations and navigation. These impacts mainly depend on the iceberg volume, which remains an elusive parameter to measure. We investigate the
D. O. Dammann +9 more
doaj +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Bistatic SAR experiments with the TanDEM-X constellation [PDF]
Launched in June 2010, TanDEM-X is an interferometric mission with the main goal of providing a high-resolution, global and unprecedentedly accurate digital elevation model (DEM) of the Earth by means of single-pass X-band SAR interferometry. Despite its usual quasi-monostatic configuration, TanDEM-X is the first genuinely bistatic SAR system in space.
Marc Rodriguez-Cassola +11 more
openaire +2 more sources
EXTRACTION OF BUILIDNG SHAPE FROM TANDEM-X DATA [PDF]
Large scale mapping and modeling of urban areas is requested in many fields, especially in planning of energy supply and for change detection. For this purpose, SAR systems are highly attractive due to their independency of daytime and weather.
A. Thiele +4 more
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source

