Results 221 to 230 of about 1,311,167 (255)

Integrating efficient and tailored perovskite and organic solar cells into performance-improved tandem photovoltaics. [PDF]

Chem Sci
Liu L, Huang X, Jen AK.
europepmc   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Direct Identification and Quantification of Flavonoids and Their Structural Isomers Using Ambient Ionization Tandem Mass Spectrometry. [PDF]

Rapid Commun Mass Spectrom
Wang Y, Xu L, Gu T, Li H, Chen DDY.
europepmc   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

Telomere‐to‐Telomere Genomes Reveal that Multiscale Evolution Shapes the Largest Metabolic Arsenal of Diaporthe Fungi

Advanced Science, EarlyView.
This study presents the first telomere‐to‐telomere genomes and population resources for Diaporthe pathogens, uncovering the largest known fungal repertoire of secondary metabolite gene clusters. Structural variations and horizontal gene transfer drive cluster diversification, while specific rapidly evolving clusters control virulence, offering novel ...
Kainan Li, Chen Zhang, Zhichao Zhang, Jiaheng Cheng, Qiuyan Gao, Long Gao, Xiaolin Zhao, Wei Yan, Yuanchao Wang, Wenwu Ye   +9 more
wiley   +1 more source

H3K4me1 directs H3K36me2 and H3K36me3 deposition in land plants. [PDF]

Nat Commun
Wu J, Wang J, Du K, Li Y, Xie W, He C, Xing Q, Li X, Zhu X, Wu Z, Wu X, Zhang L, Shen WH, Lan F, Gan J, Liu B, Dong A.   +16 more
europepmc   +1 more source

Mass Spectrometry Imaging‐Assisted Discovery of Gallotannin Biosynthetic Genes in the Root of Paeonia suffruticosa

Advanced Science, EarlyView.
An integrated approach combining mass spectrometry imaging, transcriptomics, and phylogenetic analysis facilitated the efficient identification of genes involved in gallotannin biosynthesis in Paeonia suffruticosa. As a result, a key UGT and several SCPL acyltransferases responsible for biosynthesizing pentagalloylglucose were successfully identified ...
Yushi Liu, Wenna Duan, Weiwei Tang, Yucheng Zhao, Bin Li   +4 more
wiley   +1 more source

Selection of hybrid applicators for adaptive cervical cancer brachytherapy: A practical guide. [PDF]

J Contemp Brachytherapy
Kilar CR, Bajwa HK, Pifer PM, Beriwal S.
europepmc   +1 more source

Cation-Anion Synergy Enables Uniform and Stable SAMs for High-Efficiency Perovskite/TOPCon Tandem Solar Cells. [PDF]

Adv Sci (Weinh)
Ma H, Li X, Li H, Guan J, Zheng L, Wu J, He Z, Yu Y, Wang J, Yang J, Zhang X, Zhang M, Zeng Y, Xu M, Ying Z, Yang X, Ye J.   +16 more
europepmc   +1 more source

The sensitivity of TANDEM - A new measure of trauma competence. [PDF]

PLoS One
Gjestad R, Nordanger DØ, Coman A, Yttri AM.   +3 more
europepmc   +1 more source