Results 31 to 40 of about 1,298,335 (305)

TANDEM: understanding diabetes and tuberculosis [PDF]

open access: yesThe Lancet Diabetes & Endocrinology, 2014
Dockrell HM, Eckold CE, Cliff JM, Moore D, Griffiths UK, Laurence YV, van Crevel R, Netea MG, Aarnoutse R, Kaufmann SH, Beigier-Bompadre M, Leitner S, Löwe D, Golinski R, Ottenhoff TH, Haks MC, Joosten SA, Vrieling F, Walzl G, Ronacher K, Malherbe S, van der Spuy G, Critchley JA, Kerry SR, Pearson F, Hill PC, McAllister SM, Ioana M, Panduru NM, Riza AL,
van Crevel, R.   +7 more
openaire   +6 more sources

Determination of Creatinine in Human Urine with Flow Injection Tandem Mass Spectrometry [PDF]

open access: yes, 2012
Background/Aims: Excretion of urinary compounds in spot urine is often estimated relative to creatinine. For the growing number of liquid chromatography-tandem mass spectrometry (LC-MS/MS) assays of urine-excreted molecules, a fast and accurate method ...
Koletzko, Berthold   +2 more
core   +1 more source

QM/MM methods in studies of coinage metals: copper, silver, and gold interacting with biological and organic molecules

open access: yesAdvances in Physics: X, 2023
A QM/MM method is an atomistic simulation algorithm that allows researchers to describe different regions of a system with different physical laws. Here, we review this hybrid method’s applications to the study of copper, silver, and gold atoms and ...
O. Lopez-Acevedo, D. Sucerquia
doaj   +1 more source

Abolishing Retro-Transduction of Producer Cells in Lentiviral Vector Manufacturing

open access: yesViruses
Transduction of producer cells during lentiviral vector (LVV) production causes the loss of 70–90% of viable particles. This process is called retro-transduction and it is a consequence of the interaction between the LVV envelope protein, VSV-G, and the ...
Soledad Banos-Mateos   +9 more
doaj   +1 more source

A Bayesian approach to extracting free-energy profiles from cryo-electron microscopy experiments

open access: yesScientific Reports, 2021
Cryo-electron microscopy (cryo-EM) extracts single-particle density projections of individual biomolecules. Although cryo-EM is widely used for 3D reconstruction, due to its single-particle nature it has the potential to provide information about a ...
Julian Giraldo-Barreto   +6 more
doaj   +1 more source

Pitfall in the high-throughput quantification of whole blood cyclosporin A using liquid chromatography-tandem mass spectrometry [PDF]

open access: yes, 2005
In a growing number of laboratories the technique of liquid chromatography-tandem mass spectrometry is used for the quantification of cyclosporin A in whole blood, employing cyclosporin D as the internal standard. Cyclosporin A is extensively metabolized
Spöhrer, Ute, Vogeser, Michael
core   +1 more source

Establishment and Characterization of a Stable Producer Cell Line Generation Platform for the Manufacturing of Clinical-Grade Lentiviral Vectors

open access: yesBiomedicines
Background/Objectives: To date, nearly 300 lentiviral-based gene therapy clinical trials have been conducted, with eight therapies receiving regulatory approval for commercialization.
Ane Arrasate   +12 more
doaj   +1 more source

Tournant social des dispositifs d'apprentissage des langues en autoformation – Un exemple de dispositif pour le russe

open access: yesALSIC: Apprentissage des Langues et Systèmes d'Information et de Communication, 2019
Nous proposons dans cet article de présenter un dispositif institutionnel d'apprentissage en autoformation du russe au Cnam, adapté d'un dispositif d'autoformation en langues implanté il y a 30 ans dans le même établissement.
Elsa Chachkine
doaj   +1 more source

Comparative Analysis of Tandem Repeats from Hundreds of Species Reveals Unique Insights into Centromere Evolution [PDF]

open access: yes, 2012
Centromeres are essential for chromosome segregation, yet their DNA sequences evolve rapidly. In most animals and plants that have been studied, centromeres contain megabase-scale arrays of tandem repeats.
Bradnam, Keith R.   +16 more
core   +4 more sources

A polymer tandem solar cell with 10.6% power conversion efficiency. [PDF]

open access: yes, 2013
An effective way to improve polymer solar cell efficiency is to use a tandem structure, as a broader part of the spectrum of solar radiation is used and the thermalization loss of photon energy is minimized.
Chen, Chun-Chao   +10 more
core   +1 more source

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