Results 61 to 70 of about 1,311,167 (255)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Self‐assembled monolayers (SAMs) in inverted perovskite solar cells and their tandem photovoltaics application

open access: yesInterdisciplinary Materials
Self‐assembled monolayers (SAMs) employed in inverted perovskite solar cells (PSCs) have achieved groundbreaking progress in device efficiency and stability for both single‐junction and tandem configurations, owing to their distinctive and versatile ...
Zijun Yi   +13 more
doaj   +1 more source

STAGES OF TEACHING POST-GRADUATE STUDENTS RESEARCH WRITING DISCOURSE USING THE TANDEM-METHOD

open access: yesВестник Тамбовского университета. Серия: Гуманитарные науки, 2016
The development of foreign language teaching algorithm research discourse of post-graduate students on the basis of the tandem method is prepared. The results of the research are a) an analysis of studies on the implementation of the project methodology ...
Oksana Olegovna Amerkhanova
doaj   +1 more source

One-pot radioiodination of aryl amines via stable diazonium salts: preparation of 125I-imaging agents [PDF]

open access: yes, 2017
An operationally simple, one-pot, two-step tandem procedure that allows the incorporation of radioactive iodine into aryl amines via stable diazonium salts is described.
Luthra, Sajinder K.   +4 more
core   +2 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Effect of top cell absorber thickness and bifacial illumination on monolithic (Ag,Cu)(In,Ga)Se2/Si tandem solar cells

open access: yesJPhys Energy
Wide bandgap (Ag,Cu)(In,Ga)Se _2 (ACIGSe) is a viable candidate as top cell absorber in tandem devices. In this work, we investigate monolithic two-terminal ACIGSe-Si tandem cells with a bandgap of 1.5 eV.
Julia Horstmann   +5 more
doaj   +1 more source

InP/Ga0.47In0.53As monolithic, two-junction, three-terminal tandem solar cells [PDF]

open access: yes
The work presented has focussed on increasing the efficiency of InP-based solar cells through the development of a high-performance InP/Ga(0.47)In(0.53)As two-junction, three-terminal monolithic tandem cell.
Coutts, T. J.   +4 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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