Results 1 to 10 of about 31,885 (149)

Recognition of a tandem lesion by DNA bacterial formamidopyrimidine glycosylases explored combining molecular dynamics and machine learning [PDF]

Computational and Structural Biotechnology Journal, 2021
International audienceThe combination of several closely spaced DNA lesions, which can be induced by a single radical hit, constitutes a hallmark in the DNA damage landscape and radiation chemistry.
Emmanuelle Bignon, Natacha Gillet, Antonio Monari   +2 more
exaly   +3 more sources

Traceless Tandem Lesion Formation in DNA from a Nitrogen-Centered Purine Radical [PDF]

Journal of the American Chemical Society, 2018
Nitrogen-centered nucleoside radicals are commonly produced reactive intermediates in DNA exposed to γ-radiolysis and oxidants, but their reactivity is not well understood.
Liwei Zheng, Marc M Greenberg
exaly   +3 more sources

Safety and Efficacy of Tenecteplase and Alteplase in Patients With Tandem Lesion Stroke: A Post Hoc Analysis of the EXTEND-IA TNK Trials. [PDF]

Neurology, 2023
Safety and Efficacy of Tenecteplase and Alteplase in Patients With Tandem Lesion Stroke: A Post Hoc Analysis of the EXTEND-IA TNK ...
Yogendrakumar V, Churilov L, Mitchell PJ, Kleinig TJ, Yassi N, Thijs V, Wu T, Shah D, Bailey P, Dewey HM, Choi PMC, Ma A, Wijeratne T, Garcia-Esperon C, Cloud G, Chandra RV, Cordato DJ, Yan B, Sharma G, Desmond PM, Parsons MW, Donnan GA, Davis SM, Campbell BCV, EXTEND-IA TNK Investigators.   +24 more
europepmc   +2 more sources

Abstract Number ‐ 75: Simultaneous Extracranial‐Intracranial Management of Tandem Lesion (Seimless Technique) in Posterior Circulation Stroke

Stroke Vasc Interv Neurol, 2023
Introduction Simultaneous extracranial‐intracranial management of Tandem lesion in stroke (Seimless technique) is well published and important technique in treating tandem lesions in anterior circulation.
Kareemchaubal S, Kareem M, Lin E, Zaidat O.   +3 more
europepmc   +2 more sources

Mechanical Thrombectomy for Tandem Occlusions of the Internal Carotid Artery—Results of a Conservative Approach for the Extracranial Lesion [PDF]

Frontiers in Neurology, 2018
Background: Mechanical thrombectomy (MT) is of clinical benefit for patients with extracranial-intracranial tandem lesions of anterior circulation. However, the optimal approach to the cervical lesion of the internal carotid artery (ICA) during MT has ...
Pierre-François Manceau, Serge Bakchine, Sébastien Soize   +2 more
exaly   +2 more sources

PICASSO (Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem Lesion or Local Occlusion)  Thrombectomy Randomized Trial: Study Protocol and Rationale. [PDF]

Stroke Vasc Interv Neurol
Background The optimal treatment of acute large vessel occlusion with concomitant extracranial steno‐occlusive disease of the internal carotid artery remains unclear. The PICASSO (Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local
Al Kasab S, Nguyen TN, Abdalkader M, Rai A, Boo S, Kass-Hout T, Hurley M, Sultan-Qurraie A, Lin E, Given C, Elijovich L, Badruddin A, Janjua N, Jung R, Khandelwal P, Southwood C, Majjhoo A, Guerrero WR, Mueller-Kronast N, Alshekhlee A, Martinez-Gutierrez JC, Ezzeldin M, Cress M, Niazi M, Paul A, Snelling B, Razak A, Grandhi R, Morgan L, Settecase F, English J, Fernandez P, Zacharatos H, Alexander M, Asif K, Kicielinski KP, Cuellar H, Limaye K, Abraham M, Yaghi S, de Havenon A, Almekhlafi M, Linfante I, Teleb MS, Thomalla G, Gress DR, Smith WS, Brown S, Olvany J, Ibrahim L, Khan N, Zaidat OO.   +51 more
europepmc   +2 more sources

Value of intravenous alteplase before thrombectomy among patients with tandem lesions and emergent carotid artery stenting: A subgroup analysis of the SWIFT DIRECT trial [PDF]

European Journal of Neurology
BACKGROUND AND PURPOSE The value of intravenous thrombolysis (IVT) in eligible tandem lesion patients undergoing endovascular treatment (EVT) is unknown.
Adnan Mujanović, David J Seiffge, Thomas R Meinel   +2 more
exaly   +2 more sources

Triple platelet inhibition in intracranial thrombectomy with additional acute cervical stent angioplasty due to tandem lesion: a retrospective single-center analysis. [PDF]

BMC Neurol
BACKGROUND Acute stroke treatment with intracranial thrombectomy and treatment of ipsilateral carotid artery stenosis/occlusion ("tandem lesion", TL) in one session is considered safe.
Khanafer A, Henkes H, Bücke P, Hennersdorf F, Bäzner H, Forsting M, von Gottberg P.   +6 more
europepmc   +2 more sources

Diagnosis and management of tandem occlusion in acute ischemic stroke

European Journal of Radiology Open, 2023
Approximately 20–30% of patients with acute ischemic stroke, caused by large intracranial vessel occlusion, have a tandem lesion, defined as simultaneous presence of high-grade stenosis or occlusion of the cervical internal carotid artery and ...
F Giordano, Massimo Muto, Gianluigi Guarnieri   +2 more
exaly   +2 more sources

Ostial common carotid artery occlusion and balloon-mounted stenting: Implication of embolic protection device in tandem lesion [PDF]

Radiology Case Reports, 2021
Takashi Mizowaki, Atsushi Fujita, Masahiro Nakahara   +2 more
exaly   +2 more sources