Results 211 to 220 of about 545,606 (302)

Clinical Translation of Patient‐Derived Organoids: Perspectives for Personalized Therapy in Cancer

International Journal of Cancer, EarlyView.
ABSTRACT Patient‐derived organoids (PDO) are accelerating precision medicine. These biological platforms allow for the autologous in vitro expansion of material from cancer patients in a considerably short period of time. These three‐dimensional models can faithfully recapitulate aspects of tissue heterogeneity, architecture, and relevant cellular ...
Haiyan Yue, Daniele Carchidi, Philipp Schmucker, Roland Seiler, Bernhard Kiss, Catarina Macedo‐Silva, Marianna Kruithof‐de Julio   +6 more
wiley   +1 more source

The Role of Computational Models in the Detection of Colorectal Carcinoma and Precancerous Lesions. [PDF]

Int J Mol Sci
Zivic J, Jakovljevic S, Zivic M, Rancic A, Radojevic D, Maksic M, Ilic I, Milutinovic N, Mirkovic N, Eric S, Stojanovic B, Stolic R, Antonelli G, Zdravkovic N.   +13 more
europepmc   +1 more source

α2,3‐Sialyltransferase (ST3Gal1) regulates endometrioid‐type epithelial ovarian cancer cell migration and invasion via VEGF‐R2/JAK2/STAT3 signaling cascades

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To investigate the role of ST3 β‐galactoside α‐2,3‐sialyltransferase 1 (ST3Gal1) and vascular endothelial growth factor receptor 2 (VEGF‐R2) in endometrioid‐type epithelial ovarian cancer (E‐OC) because aberrant α2,3‐sialylation mediated by ST3Gal1 and VEGF‐R2‐related angiogenesis is linked with tumor progression. Methods ST3Gal1 and
Wei‐Ting Chao, Chia‐Hao Liu, Szu‐Ting Yang, Chen‐Hao Lin, Liang‐Wei Wang, Peng‐Hui Wang   +5 more
wiley   +1 more source

Endovascular treatment of tandem lesions in a novel cadaveric stroke model

EuroIntervention
Grunwald, Iris Q., Tekieli, Łukasz, Podlasek, Anna, Donald-Simpson, Helen, Clark, Stephanie, Voutsas, Chloe, Pillai, Sanjay, Houston, Graeme, Knapik, Magdalena, White, Leah, Barr, Pamela, Melzer, Andreas, Musiałek, Piotr   +12 more
openaire   +4 more sources

Surgical Indications of Carotid Endarterectomy for Patients with Tandem Lesion

Nosotchu no Geka Kenkyukai koenshu, 1980
Ono, Hirohisa, Yokoyama, Hiroaki, Mori, Kazuo   +2 more
openaire   +1 more source

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

iMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu, Xiaoyan Chen, Zichang Chen, Yalun Liang, Gokhan Zengin, Qian Zhang, Wenlong Sun, Meng‐Yao Li   +7 more
wiley   +1 more source

The Impact of Artificial Intelligence-Assisted Endoscopy on the Detection of Upper Gastrointestinal Neoplasms: A Systematic Review and Meta-Analyses. [PDF]

Dig Endosc
Liu M, Ma M, Zhang D, Zeng Y, Liang X, Lu J.   +5 more
europepmc   +1 more source

A Pan‐Cancer Single‐Cell Atlas of Bone Metastases Reveals Convergent Malignant Programs and Coordinated Immune Dysfunction

iMetaMed, EarlyView.
A pan‐cancer atlas deciphers tumor‐induced reprogramming in bone metastases. Malignant evolution toward MYC/proliferation is a hallmark of bone metastases. Niche‐mediated immune dysfunction is characterized by immature pDCs, impaired antigen presentation and phagocytosis in TAMs, and exhausted T cells.
Yitong Pan, Zhou Yang, Junyuan Deng, Feng Liu, Guang Lei   +4 more
wiley   +1 more source

Angiographically occult in-stent protrusion detected by intravascular ultrasound during carotid artery stenting: a case report. [PDF]

J Med Case Rep
Tsurumi Y, Tsurumi A, Yokoyama H, Kikuchi N, Zako R, Ishikawa T, Hososhima O.   +6 more
europepmc   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source