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Validation of Functional State of Coronary Tandem Lesions Using Computational Flow Dynamics
The American Journal of Cardiology, 2012Functional lesion assessment for coronary tandem lesions and its clinical applications have not been thoroughly studied. The aim of this study was to test the hypothesis that the fractional flow reserve (FFR) gradient across an individual stenosis (ΔFFR) during pressure-wire pullback is a surrogate of the relative functional severity of each stenosis ...
Park, Seung Jung +14 more
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Theoretical study of the tandem cross-linkage lesion in DNA
Chemical Physics Letters, 2006Abstract The intramolecular radical cross-link reactions of 8,5′-cyclo-purines and 6,5′-cyclo-pyrimidines have been studied using the DFT B3LYP formalism with 6-31+G(d,p) and 6-311++G(d,p) basis sets, and including CPCM bulk solvation effects. In aqueous solution, the largest free energy barrier is 11.1 kcal/mol for dT → 6,5′-cycloT and the ...
Ru bo Zhang, Leif A. Eriksson
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Case report. Tandem lesions: chromophobe adenoma and meningioma.
Journal of computer assisted tomography, 1978A number of cases of multiple primary intracranial neoplasms have been reported, including tumors of neuroepithelial and mesenchymal origin. The presence of meniogioma has been reported in association with glioblastoma, oligodendroglioma, astrocytoma, and eosinophilic adenoma.
T G, Brennan +3 more
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Targeted lesions of soft animal tissues induced by tandem shockwaves
2010 Abstracts IEEE International Conference on Plasma Science, 2010The success of the extracorporeal shock wave lithotripsy in non-invasive treating patients with stone deceases (mostly kidney stones) stimulated research on applications of focused shock waves in other branches of medicine such as for noninvasive treatment of cancer tissues and a targeted drug delivery.
P. Lukes +6 more
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Anesthetic management for large vessel occlusion acute ischemic stroke with tandem lesions
Journal of NeuroInterventional SurgeryBackground Endovascular therapy (EVT) stands as an established and effective intervention for acute ischemic stroke in patients harboring tandem lesions (TLs). However, the optimal anesthetic strategy for EVT in TL patients remains unclear.
Mudassir Farooqui +35 more
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Radiation-induced formation of tandem lesions: mechanistic aspect
2015During the last three decades considerable efforts have been made to determine the nature and quantify the amount of lesions produced in double stranded (ds)DNA exposed to oxidative stress. Nowadays, an almost complete decomposition pathway of the four DNA bases mediated by hydroxyl radicals and one electron-oxidation, the two damaging species of such ...
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Molecular dynamics investigation of DNA tandem lesions repair
2017DNA integrity is constantly threatened by radicals and sunlight, leading to chemical modifications of nucleobases. For two neighboring simple DNA defects, the repair turns out to be dramatically lowered [1]. However the field suffers from X-ray or NMR structure to interpret the repair rate measurements of such tandem lesions (10% of the total 8 ...
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