Results 101 to 110 of about 4,297,069 (302)

A Self‐Cleaning Solar Evaporator Based on MXene/Aramid Nanofiber Aerogels for Efficient Water Desalination

Advanced Materials Interfaces, EarlyView.
This study develops a self‐cleaning solar evaporator based on MXene‐coated aramid nanofiber aerogels for efficient desalination under high‐salinity conditions. The cylindrical evaporator combines strong photothermal conversion, capillary water transport, and self‐rotation triggered by salt accumulation.
Mandeep Singh, Si (Alex) Qin, Ken Aldren S. Usman, Yuxi Ma, Dan Liu, Weiwei Lei   +5 more
wiley   +1 more source

Region‐Specific Profiling of the Gut Microbiome and Metabolite Landscape in Response to Dietary Intervention Using Electronics‐Free Ingestible Smart Sampling Capsules

Advanced Materials Technologies, EarlyView.
Region‐specific profiling of the gut microbiome is achieved non‐invasively using electronics‐free ingestible sampling capsules that activate at defined intestinal sites through stimuli‐responsive coatings. Deployed in a porcine dietary intervention model, the capsules resolve spatially distinct, fiber‐driven shifts in microbial composition and short ...
Devendra Sarnaik, Caitlyn Sullivan, Akshay Krishnakumar, Fangxin Chen, Anna Clapp Organski, Wayne W. Campbell, Jay S. Johnson, Tzu‐Wen L. Cross, Rahim Rahimi   +8 more
wiley   +1 more source

Recent applications of liquid chromatography tandem mass spectrometry at various stages of drug development

Future Journal of Pharmaceutical Sciences
Background Liquid chromatography–tandem mass spectrometry is a combination of liquid chromatography and mass spectrometry. In this process, high-performance liquid chromatography separates analytes, ionizes them, and then analyzes them using mass filters
Sunita Sunil Gagare, Vaishnavi Bhau Thorat, Ashish Suresh Jain   +2 more
doaj   +1 more source

FIELD DESORPTION MASS-SPECTROMETRY, FAST-ATOM-BOMBARDMENT MASS-SPECTROMETRY AND FAST-ATOM-BOMBARDMENT TANDEM MASS-SPECTROMETRY OF ECHINACOSIDE, THE MAIN CAFFEOYL-GLYCOSIDE FROM ECHINACEA-ANGUSTIFOLIA ROOTS (ASTERACEAE)

, 1991
The mass spectral fragmentation of echinacoside, a pharmacologically active caffeoyl-glycoside isolated from Echinacea angustifolia roots, has been investigated using different soft-ionization techniques, field desorption and fast atom bombardment ...
B. Gioia, R. Maffei Facino, E. Arlandini, A. Sparatore, L. Franzoi, M. Carini, Bruno Gioia, Marina Carini, Emanuele Arlandini, Luigi Franzoi, Roberto Maffei Facino, Anna Sparatore   +11 more
core   +1 more source

An Anti‐Amyloidogenic Approach to Specifically Block Memory Consolidation in Mice for Therapeutic Intervention

Advanced Science, EarlyView.
Functional amyloid conversion of the translation regulator CPEB3 is essential for long‐term memory persistence. This study demonstrates that targeting this molecular switch with the anti‐amyloidogenic peptide QBP1 selectively blocks CPEB3 fibrillation without disrupting phase separation.
Paula López‐García, Kerry R. McGreevy, Maria Eugenia Vaquero, Juan M. Suarez‐Rivero, Antonio Moreno‐Rodríguez, Antonio J. Pérez‐Pulido, Daniel Ramírez de Mingo, Anna Pallé, Helena Akiko Popiel, Andrea Santi, Mario D. Cordero, José Luis Trejo, Yoshitaka Nagai, Mariano Carrión‐Vázquez   +13 more
wiley   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Single-cell MALDI Tandem Mass Spectrometry: Unambiguous Assignment of Small Biomolecules from Single Chlamydomonas reinhardtii Cells

CHIMIA, 2016
The analysis of compounds from single cells is a major challenge in analytical life science. Labeling strategies, for instance fluorescence detection, are well established for measuring proteins with single cell sensitivity, but they mostly fail
Jasmin Krismer, Robert F. Steinhoff, Renato Zenobi   +2 more
doaj   +1 more source

Identification of caffeine and its metabolites in human urine extracts by electron ionization tandem spectrometry

, 1991
Electron impact ionized purine bases such as caffeine and its metabolites (theophylline, theobromine, paraxanthine, 1-methylxanthine, 3-methylxanthine and 7-methylxanthine) were characterized by tandem mass spectrometry.
PORCELLI, BRUNETTA, LIGUORI A., MASCARO P., UCCELLA N., SINDONA G., G. Sindona, P. Mascaro, N. Uccella, A. Liguori, B. Porcelli   +9 more
core   +1 more source

Phosphorylated STYK1 Promotes Gemcitabine Resistance via Autophagy‐Mediated Cancer Stemness in Pancreatic Cancer

Advanced Science, EarlyView.
Gemcitabine resistance remains a major challenge in pancreatic ductal adenocarcinoma. This study identifies STYK1 as a key mediator of chemoresistance through autophagy‐dependent maintenance of cancer stemness. Gemcitabine‐activated AMPK phosphorylates STYK1 at Ser91 and Ser304, enhancing autophagy and stemness.
Xueying Dong, Shi Li, Chensong Huang, Xuehong Qian, Jieyu Guo, Yahao Guo, Guifang Wu, Qi Zhang, Hongfei Tan, Yu Han, Rui Zhang, Hao Lyu, Shuai Xiao, Dong Guo, Chaojun Yan, Wenying Qin, Changchun Li, Xing‐Zhen Chen, Ying Zhao, Cefan Zhou, Jingfeng Tang   +20 more
wiley   +1 more source

Tandem mass spectrometry: A primer

, 1996
Tandem mass spectrometry (MS/MS) employs two stages of mass analysis in order to examine selectively the fragmentation of particular ions in a mixture of ions.
PANDOLFO, LUCIANO, PAIARO G, TRALDI P., CATINELLA S, Guevremont, R., de Hoffmann, Edmond, Ke, F., Wang, J., Siu, K. W.M.   +8 more
core   +1 more source