Results 31 to 40 of about 259,902 (261)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
EXTRACTION OF BUILIDNG SHAPE FROM TANDEM-X DATA [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2013 Large scale mapping and modeling of urban areas is requested in many fields, especially in planning of energy supply and for change detection. For this purpose, SAR systems are highly attractive due to their independency of daytime and weather.
A. Thiele +4 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Evolving the Operations of the TerraSAR-X / TanDEM-X Mission Planning System during the TanDEM-X Science Phase [PDF]
SpaceOps 2016 Conference, 2016 After the successful Global Coverage of the Digital Elevation Model, the TanDEM-X Science phase was initiated in September of 2014, dedicated to the demonstration of innovative techniques and experiments. The TanDEM-X Science phase had a large impact on the TerraSAR-X/TanDEM-X Mission Planning System.
Stathopoulos, Fotios +4 more
openaire +2 more sources
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Challanges of the TanDEM-X Commissioning Phase [PDF]
, 2010 The paper describes the execution of the TanDEM-X commissioning phase. It provides the challanges and constraints of the different tasks and their impact on each other during the commissioning phase. In addition, the paper gives information about the tasks to be performed.
Bachmann, Markus, Hofmann, Harald
openaire +1 more source
Coastal Assessment of Sentinel-6 Altimetry Data during the Tandem Phase with Jason-3
Remote Sensing, 2023 This study presents a comparative analysis of the coastal performances of Sentinel-6 and Jason-3 altimeters during their tandem phase, considering their different processing modes.
Marcello Passaro +4 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source