Results 51 to 60 of about 249,250 (259)

A Novel Tandem Differential Edge Sensor Layout for Segmented Mirror Telescopes

Sensors, 2023
The performance of an active control system, crucial for the co-phase maintenance of segmented mirrors, is closely related to the spatial layout of sensors and actuators.
Yinlong Huo, Fei Yang, Fuguo Wang, Peng Guo, Jiakang Zhu, Yuanguo Liu   +5 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Using TanDEM-X Pursuit Monostatic Observations with a Large Perpendicular Baseline to Extract Glacial Topography

Remote Sensing, 2018
Space-based Interferometric Synthetic Aperture Radar (InSAR) applications have been widely used to monitor the cryosphere over past decades. Owing to temporal decorrelation, interferometric coherence often severely degrades on fast moving glaciers ...
Sang-Hoon Hong, Shimon Wdowinski, Falk Amelung, Hyun-Cheol Kim, Joong-Sun Won, Sang-Wan Kim   +5 more
doaj   +1 more source

Two-Moment Phase-Type Fitting for ASIP Tandem Systems

Proceedings of the 15th International Conference on Operations Research and Enterprise Systems
The asymmetric simple inclusion process (ASIP) is an n-site tandem stochastic network used to model clustered particle flow. Particles at each site form a cluster that moves to the next site when its gate opens. For the general ASIP, no closed-form expression exists for the load in terms of the first two moments of the interarrival and inter-gate ...
Geelen, Wesley, Vlasiou, Maria
openaire   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Towards the Analysis of the Performance Measures of Heterogeneous Networks by Means of Two-Phase Queueing Systems

Discrete and Continuous Models and Applied Computational Science, 2021
Due to a multistage nature of transmission processes in heterogeneous 4G, 5G mobile networks, multiphase queuing systems become one of the most suitable ways for the resource allocation algorithms analysis and network investigation.
Tatiana Rykova
doaj  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Unconventional phase metal heteronanostructures with tunable exposed interface for efficient tandem nitrate electroreduction to ammonia

Nature Communications
Tandem catalysis is an effective approach to achieve highly selective and high-rate multi-electron/proton transfer reactions, such as nitrate electroreduction, which are important for various physicochemical and biological processes.
Yangbo Ma, Liang Guo, Liang Chang, Weihua Guo, Tao Zhou, Fengkun Hao, Wenda Su, Jingwen Zhou, Guozhi Wang, Mingzheng Shao, Jihan Yu, Jinwen Yin, Yunhao Wang, Fu Liu, An Zhang, Kun Qian, Jie Wang, Xiuyun Zhang, Weijia Zhou, Shengqi Chu, Chongyi Ling, Lin Gan, Zhengxiao Guo, Zhanxi Fan   +23 more
doaj   +1 more source

Data for Tandem Mass Tag (TMT) proteomic analysis of the pancreas during the early phase of experimental pancreatitis

Data in Brief, 2018
The quantitative proteomics data reported here pertain to the research article entitled “A Tandem Mass Tag (TMT) proteomic analysis during the early phase of experimental pancreatitis reveals new insights in the disease pathogenesis” (García-Hernández et
Violeta García-Hernández, Carmen Sánchez-Bernal, Domitille Schvartz, José J. Calvo, Jean-Charles Sanchez, Jesús Sánchez-Yagüe   +5 more
doaj   +1 more source