Results 51 to 60 of about 259,902 (261)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Phase I study of sorafenib in patients with refractory or relapsed acute leukemias
Haematologica, 2011 Background Sorafenib is a multi-kinase inhibitor with activity against fms-like tyrosine kinase 3 with internal tandem duplication mutation and Raf kinase among others.
Gautam Borthakur +10 more
doaj +1 more source
Scientific Reports, 2021 Tandem gait is considered one of the most useful screening tools for gait impairment. The aim of this study is to evaluate diagnostic usefulness of 10-step tandem gait test for the patients with degenerative cervical myelopathy (DCM).
Dallah Yoo +4 more
doaj +1 more source
Phase unwrapping correction with dual-baseline data for the TanDEM-X mission [PDF]
2012 IEEE International Geoscience and Remote Sensing Symposium, 2012 The operational dual-baseline phase unwrapping algorithm for the TanDEM-X mission is based on a combination of separate single-baseline phase unwrapping and a correction procedure of different levels of complexity. It benefits from all the information available from the two TanDEM-X acquisitions by computing a differential interferogram to obtain a ...
Lachaise, Marie +4 more
openaire +2 more sources
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Discrete and Continuous Models and Applied Computational Science, 2021 Due to a multistage nature of transmission processes in heterogeneous 4G, 5G mobile networks, multiphase queuing systems become one of the most suitable ways for the resource allocation algorithms analysis and network investigation.
Tatiana Rykova
doaj
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Data in Brief, 2018 The quantitative proteomics data reported here pertain to the research article entitled “A Tandem Mass Tag (TMT) proteomic analysis during the early phase of experimental pancreatitis reveals new insights in the disease pathogenesis” (García-Hernández et
Violeta García-Hernández +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Nature CommunicationsTandem catalysis is an effective approach to achieve highly selective and high-rate multi-electron/proton transfer reactions, such as nitrate electroreduction, which are important for various physicochemical and biological processes.
Yangbo Ma +23 more
doaj +1 more source