Results 251 to 260 of about 136,753 (311)

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

A PDZ tandem repeat folds and unfolds via different pathways. [PDF]

Protein Sci
Pennacchietti V, di Matteo S, Pagano L, Toplek FB, Stegani B, Toto A, Toso J, Puglisi E, Capelli R, Di Felice M, Malagrinò F, Camilloni C, Gianni S.   +12 more
europepmc   +1 more source

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

Advanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng, Zongbi Yi, Jing Hu, Jiali Li, Yu Xu, Xiuli Guo, Qian Ji, Kaixiang Feng, Ying Zhang, Sirui Bai, Yushuang Tan, Yufei Yan, Linzhi Han, Jing Jiang, Tengfei Wang, Xiang Wang, Ziqing Zhan, Ruiying Huang, Jinfang Zhang, Conghua Xie, Binghe Xu   +20 more
wiley   +1 more source

Modeling Short Tandem Repeat (STR) DNA Fingerprinting Using Standard Playing Cards

Amy L. Klocko
openalex   +1 more source

Uterine teratoma and the role of short-tandem repeat genotyping in understanding origins. [PDF]

Gynecol Oncol Rep
AlAshqar A, Kadam Maruthi V, Abi-Raad R, Greenman M, Hui P, Ratner E, Altwerger G, Santin A, Andikyan V.   +8 more
europepmc   +1 more source

A genome-wide spectrum of tandem repeat expansions in 338,963 humans. [PDF]

Cell
Cui Y, Ye W, Li JS, Li JJ, Vilain E, Sallam T, Li W.   +6 more
europepmc   +1 more source

Tandem-repeat proteins introduce tuneable properties to engineered biomolecular condensates. [PDF]

Chem Sci
Ng TLC, Hoare MP, Maristany MJ, Wilde EJ, Sneideris T, Huertas J, Agbetiameh BK, Furukawa M, Joseph JA, Knowles TPJ, Collepardo-Guevara R, Itzhaki LS, Kumita JR.   +12 more
europepmc   +1 more source

Evaluation of mtDNA analysis as a screening method prior to individual identification by short tandem repeat analysis of sika deer (<i>Cervus nippon</i>) for illegal disposal of hunting in Japan. [PDF]

Front Vet Sci
Tanaka A, Ueda R, Udagawa C, Omi T, Kihara Y, Hayama SI.   +5 more
europepmc   +1 more source

Supramolecular Assembly and Interfacial Hydration of Tandem Repeat Dipeptides on 2D Nanomaterials: Insights From 3D-AFM Measurements and MD Simulations. [PDF]

Small
Yurtsever A, Priante F, Sun L, Sugiyama M, Miyata K, Miyazawa K, Kesornsit S, Maeda K, Foster AS, Hayamizu Y, Sarikaya M, Fukuma T.   +11 more
europepmc   +1 more source