Results 221 to 230 of about 171,839 (292)

Efficient Cell Removal and Impurity Reduction for Poxvirus Purification in a Single Step Alluvial Filtration

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Modified Vaccinia virus Ankara (MVA) is a potent vector for the development of vaccines and novel cancer treatment strategies. Since it is a non‐replicating virus in human recipients, high infective titers are required for therapeutic efficacy.
Linus G. Weber   +5 more
wiley   +1 more source

Serotype‐Tailored Midstream and Downstream Operations to Advance the Manufacturing of Adeno‐Associated Viral Vectors

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated viruses (AAVs) are the leading vectors for in vivo gene therapy, fueling a growing demand for scalable and robust biomanufacturing processes. Yet, the impact of cell lysis conditions on the performance of midstream and downstream unit operations across serotypes remains poorly characterized.
Arianna Minzoni   +20 more
wiley   +1 more source

pyFDRT: An open‐source Python tool for Fourier‐transform analysis of the distribution of relaxation times in electrochemical impedance spectra

open access: yesBulletin of the Korean Chemical Society, EarlyView.
pyFDRT is an open‐source tool that converts an impedance spectrum into a quantitative equivalent circuit. Its Fourier‐transform stage requires no discretization basis or regularization parameter, and the non‐negative refinement selects its own parameters, and an information criterion determines the relaxation process count.
Chung‐Yul Yoo   +2 more
wiley   +1 more source

Innovation of plant‐derived extracellular vesicles and interdisciplinary research: From discovery to biomedical applications

open access: yesBMEMat, EarlyView.
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li   +6 more
wiley   +1 more source

Restoring joint homeostasis: A dynamically adaptive meniscal scaffold prevents osteoarthritis by replicating native biomechanics

open access: yesBMEMat, EarlyView.
This work establishes a paradigm shift from static structural mimicry to dynamic functional replication. By restoring the native “compression‐to‐tension” mechanism, the scaffold ensures robust mechanical stability and superior chondroprotection.
Wan Li   +10 more
wiley   +1 more source

An Indicator‐Based Decision Framework for Circular Bioeconomy Transition in the Steel Industry: Integrating Multiphase Learning and Cooperative Game Modelling

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Despite growing attention to the circular bioeconomy (CBE), the steel industry currently lacks a standardised, sectoral measurement framework to facilitate a low‐carbon transition. In this study, a decision‐support framework for evaluating CBE performance in the steel industry is proposed.
Ali Zamani Babgohari   +2 more
wiley   +1 more source

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