Results 91 to 100 of about 66,955 (265)
Broń precyzyjna a czołgi – zagrożenia dla pojazdów pancernych na współczesnym polu walk [PDF]
Przegląd GeopolitycznyThe aim of the article is to discuss the threat to tanks on the contemporary battlefield posed by modern precision anti-tank weapons, illustrated through examples such as kamikaze drones, loitering munitions and guided anti-tank missiles.
Patryk Laskowski
doaj
Advanced Science, EarlyView.Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding +7 more
wiley +1 more source
Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma
Advanced Science, EarlyView.ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba +25 more
wiley +1 more source
Advanced Science, EarlyView.Bioinspired passive flow routing mitigates thrombosis in cardiovascular devices by redirecting a small fraction of forward flow into stagnation‐prone regions. Inspired by avian alula and aircraft slat mechanisms, strategically placed routing channels restore washout around mechanical heart valves, reducing low‐shear exposure by four orders of magnitude
Yevgeniy Kreinin +8 more
wiley +1 more source
Advanced Science, EarlyView.Schematic illustration of a biomimetic SKEV@AAV platform targeting p21‐high senescent Kupffer cells (sKCs) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). p21‐high sKCs accumulate in the PVTT microenvironment and establish an immunosuppressive, SASP‐rich environment that facilitates tumor cell proliferation and immune evasion.
Na Ta +10 more
wiley +1 more source
Fiyz̤, 2019 Background: Alternative synthetic estrogen replacement hormone therapy has a deleterious effect on the liver tissue. It seems the pumpkin seeds can be a good alternative to hormone therapy.
Motamed-Jahromi S , Niami-Jahromi S
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A Smart Fluid‐Hydraulic System Based on MRF Valve Control and Its Application in Flexible Grasping
Advanced Science, EarlyView.This study introduces a smart fluid hydraulic system using MRF valve control for flexible gripping. An MRF‐MSV with an integrated excitation coil and micro‐textured damping channels is designed and validated; micro‐texturing increases hydraulic resistance. Coupled with a soft actuator, the MRF‐MSV enables dynamic bending and grasping.
Linfeng Huo +5 more
wiley +1 more source
Advanced Science, EarlyView.Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng +19 more
wiley +1 more source
Thermally Assisted Photocatalytic Dehydrogenation of Methanol in Continuous Steady‐State Operation
Advanced Science, EarlyView.Thermally assisted photocatalytic methanol dehydrogenation on Pt/TiO2 enables formaldehyde and hydrogen production far beyond thermodynamic limits. Continuous operation delivers up to 95% selectivity over 70 h, and oxygen microdosing strongly boosts conversion by regenerating surface oxygen sites.
Stubenrauch Florian +8 more
wiley +1 more source