Results 171 to 180 of about 2,196 (203)
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Bacterial resistance to antibiotics: Modified target sites
Advanced Drug Delivery Reviews, 2005Alteration in the target sites of antibiotics is a common mechanism of resistance. Examples of clinical strains showing resistance can be found for every class of antibiotic, regardless of the mechanism of action. Target site changes often result from spontaneous mutation of a bacterial gene on the chromosome and selection in the presence of the ...
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Altered target sites as a mechanism of herbicide resistance
Crop Protection, 2000Abstract Over 200 distinct herbicide resistant weed biotypes have evolved worldwide. In most of these, resistance is conferred by an altered target site, i.e. a modified target protein with reduced affinity for the herbicide(s) in question. This has been documented for herbicides that target most major known sites of action, including those that ...
Malcolm D. Devine, Amit Shukla
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Non-target Site Mechanisms of Resistance to Herbicides
Critical Reviews in Plant Sciences, 2017ABSTRACTEvolution of resistance in weeds to herbicides is threatening world agricultural production. Weed management has become more complicated with the development of non-target site resistance (NTSR) to herbicides in weeds. The NTSR mechanisms can be caused by herbicide metabolism, altered patterns of translocation, and herbicide absorption ...
Hossein Ghanizadeh, Kerry C. Harrington
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R-factor trimethoprim resistance mechanism: An insusceptible target site
Biochemical and Biophysical Research Communications, 1974Abstract R-factor R388 increases the resistance of Escherichia coli to trimethoprim by 10,000 fold, and mediates the synthesis of an addional dihydrofolate reductase that is less susceptible to trimethoprim by a similar order of magnitude. The dihydrofolate reductase conferred by the R-factor was of a larger molecular weight than the wild-type ...
S G, Amyes, J T, Smith
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Pesticide Biochemistry and Physiology
Silene conoidea L., a common weed in wheat fields, is mainly controlled by acetolactate synthase (ALS)-inhibiting herbicides such as mesosulfuron-methyl. In this study, we investigated a mesosulfuron-methyl resistant population to elucidate the resistance mechanisms.
Xinhui, Xue +7 more
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Silene conoidea L., a common weed in wheat fields, is mainly controlled by acetolactate synthase (ALS)-inhibiting herbicides such as mesosulfuron-methyl. In this study, we investigated a mesosulfuron-methyl resistant population to elucidate the resistance mechanisms.
Xinhui, Xue +7 more
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New Zealand Journal of Agricultural Research
ABSTRACT Resistance to iodosulfuron, a herbicide targeting acetolactate synthase (ALS), was identified and characterised in a population of Lolium perenne L. from Canterbury, New Zealand.
Hossein Ghanizadeh +4 more
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ABSTRACT Resistance to iodosulfuron, a herbicide targeting acetolactate synthase (ALS), was identified and characterised in a population of Lolium perenne L. from Canterbury, New Zealand.
Hossein Ghanizadeh +4 more
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Weed Biology and Management, 2014
Sagittaria trifolia L. is one of the most serious weeds in paddy fields in Japan. Since the late 1990s, severe infestations of S. trifolia have occurred following applications of sulfonylurea herbicides in Akita prefecture. In this study, two accessions of S.
Satoshi Iwakami +4 more
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Sagittaria trifolia L. is one of the most serious weeds in paddy fields in Japan. Since the late 1990s, severe infestations of S. trifolia have occurred following applications of sulfonylurea herbicides in Akita prefecture. In this study, two accessions of S.
Satoshi Iwakami +4 more
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Target-site resistance to bensulfuron-methyl in Sagittaria trifolia L. populations
Pesticide Biochemistry and Physiology, 2015Sagittaria trifolia L. is one of the most serious weeds in paddy fields in northeast of China and cannot be controlled effectively by bensulfuron-methyl in recent years. In this study, two suspected resistant S. trifolia populations (R1 and R2) were collected in Liaoning province of China.
Songhong Wei +4 more
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Plant Cell Reports
Lolium multiflorum exhibits resistance to mesosulfuron-methyl through ALS mutations; HZ2 population also shows metabolic resistance through P450 pathways. Lolium multiflorum L., is a weed that frequently appears in wheat fields and is recognized for its strong competitive nature, where it can cause significant damage to grain production. The weeds of L.
Pei Zhang +5 more
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Lolium multiflorum exhibits resistance to mesosulfuron-methyl through ALS mutations; HZ2 population also shows metabolic resistance through P450 pathways. Lolium multiflorum L., is a weed that frequently appears in wheat fields and is recognized for its strong competitive nature, where it can cause significant damage to grain production. The weeds of L.
Pei Zhang +5 more
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Macrolide Resistance Conferred by Alterations in the Ribosome Target Site
2014This chapter concentrates on resistance to a subset of antibiotics, the 14-membered ring macrolides, and considers their fate as effective antibacterial agents now that resistance is widespread among bacterial pathogens. The ribosome target site for macrolides lies within the 23S rRNA at the peptidyltransferase center of the 50S subunit.
Douthwaite, Stephen, Vester, Birte
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