Results 91 to 100 of about 2,545,393 (299)

Research on Retrieval Algorithm of CAPP System Based onManufacturing Feature of Aeronautical Structural Parts

open access: yesHangkong gongcheng jinzhan, 2018
The aircraft structure is an important part of the air-frame, and its manufacturing process is complex. It is difficult to recognize the target in the computer-aided process planning(CAPP) system.
Wang Peng   +3 more
doaj   +1 more source

RAD21 amplification epigenetically suppresses interferon signaling to promote immune evasion in ovarian cancer

open access: yesThe Journal of Clinical Investigation, 2022
Prevalent copy number alteration is the most prominent genetic characteristic associated with ovarian cancer (OV) development, but its role in immune evasion has not been fully elucidated.
Peng Deng   +33 more
doaj   +1 more source

Specifying and Executing Optimizations for Parallel Programs

open access: yes, 2014
Compiler optimizations, usually expressed as rewrites on program graphs, are a core part of all modern compilers. However, even production compilers have bugs, and these bugs are difficult to detect and resolve. The problem only becomes more complex when
Griffith, Dennis   +2 more
core   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Targetting and guidance program documentation [PDF]

open access: yes
A FORTRAN computer program was developed which automatically targets two and three burn rendezvous missions and performs feedback guidance using the GUIDE algorithm.
Harrold, E. F., Neyhard, J. F.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Object-oriented Tools for Distributed Computing [PDF]

open access: yes, 1993
Distributed computing systems are proliferating, owing to the availability of powerful, affordable microcomputers and inexpensive communication networks.
Adler, Richard M.
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Microenvironment-confined kinetic elucidation and implementation of a DNA nano-phage with a shielded internal computing layer

open access: yesNature Communications
Multiple receptor analysis-based DNA molecular computation has been developed to mitigate the off-target effect caused by nonspecific expression of cell membrane receptors.
Decui Tang   +9 more
doaj   +1 more source

THE PROGRAM SUPPORT SOCIAL AND PSYCHOLOGICAL SAFETY OF CHILDREN WITH INTELLECTUAL DISABILITIES

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2018
The article presents a description of the author’s program to support the social and psychological safety of children with intellectual disabilities enrolled in boarding school of VIII kind.
Pavel Aleksandrovich Kislyakov   +3 more
doaj   +1 more source

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