Results 31 to 40 of about 382,266 (299)

Construction Cost of Chemical Plant Based on Dynamic Management Technology

open access: yesChemical Engineering Transactions, 2018
With the vigorous development of China’s chemical industry, the scale of investment in construction projects of chemical enterprises has been expanding.
Zhi Guo, Shumin Song
doaj   +1 more source

Sustainable Development Goals Data-Driven Local Policy: Focus on SDG 11 and SDG 12

open access: yesAdministrative Sciences, 2022
Municipal solid waste charging schemes can be powerful drivers for local policy efforts in reaching the goals of the 2030 Agenda for Sustainable Development adopted by all United Nations Member States in 2015.
Massimo Beccarello, Giacomo Di Foggia
doaj   +1 more source

The impact of organizational characteristics on the adoption of contemporary cost management techniques by the textile industry in North Macedonia [PDF]

open access: yesContabilitate şi Informatică de Gestiune, 2020
Research Question: What is the association between the choice of contemporary cost management methods and enterprise and employee characteristics? Motivation: Modern techniques of cost accounting assist strategic management of contemporary organization ...
Dusica Stevcevska Srbinoska   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Optimal Plan for Equipping Residential Buildings to Accessories for Reducing Water Consumption (Case Study: Isfahan City) [PDF]

open access: yesعلوم و مهندسی آب و فاضلاب, 2019
Due to role of water consumption management as a main part in demand management, installing the retrofit accessories for the house fixtures, on the technical side of water consumption management, can have a significant impact on reducing urban water ...
Asieh Sadat Mollabashi   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Prescribing patterns and pharmacoeconomic analysis of antihypertensive drugs in South Indian population: A cross-sectional study

open access: yesPerspectives in Clinical Research, 2023
Background: Global evidence-based recommendations for hypertension management are periodically updated, and ensuring adherence to the guidelines is imperative.
S Shanmugapriya   +5 more
doaj   +1 more source

MANAGING TARGET COSTS AT THE DEVELOPMENT STAGE OF A PRODUCT

open access: yesJournal of Production Engineering, 2020
At the development stage of a product, target cost management has a significant effect on achievement and maintenance of product competitiveness in a given market and the desired target profit as the primary aim of production. Target cost management, i.e., target profit management, is performed by evaluating individual variations of a conceptual and ...
Vladimir Todić   +2 more
openaire   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Developing Cost Management in Modular Product Development

open access: yes, 2023
Product development has a crucial role in developing competitive advantage. Product development must balance between functionality, quality, and cost according to the customer needs when developing new products.
Alminoja, Emmi
core  

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