Results 41 to 50 of about 1,871,993 (304)
Background: Global evidence-based recommendations for hypertension management are periodically updated, and ensuring adherence to the guidelines is imperative.
S Shanmugapriya +5 more
doaj +1 more source
MANAGING TARGET COSTS AT THE DEVELOPMENT STAGE OF A PRODUCT
At the development stage of a product, target cost management has a significant effect on achievement and maintenance of product competitiveness in a given market and the desired target profit as the primary aim of production. Target cost management, i.e., target profit management, is performed by evaluating individual variations of a conceptual and ...
Vladimir Todić +2 more
openaire +1 more source
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi +5 more
wiley +1 more source
Transfering Target Excellence Overseas: Toward a Conceptual Framework of Global Target Cost Management [PDF]
Target cost management(TCM) has become a significant issue in off-shore bases of Japanese corporation in line with globalization of product development functions in recent years. This article, instead of discussing " whether it is transferable or not",
Okano, Hiroshi
core
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Medicaid managed care: how to target efforts to reduce costs [PDF]
To be successful, cost control efforts must target Medicaid Managed Care (MMC) beneficiaries likely to incur high costs. The critical question is how to identify potential high cost beneficiaries with simple, reproducible, transparent, auditable criteria.
Charlson, Mary E +4 more
openaire +2 more sources
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
With the increasing demand for electricity in modern society, the scale of substation construction projects has greatly expanded, and the ever-increasing technical requirements have led to rising project costs year by year.
Hongyan Xin +3 more
doaj +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Target costing and activity-based costing are cost management tools that support strategic cost management in addressing these challenges, especially since this requires integrating the two technologies.
Israa Yousif Thanoon
doaj +1 more source

