Results 41 to 50 of about 1,871,993 (304)

Prescribing patterns and pharmacoeconomic analysis of antihypertensive drugs in South Indian population: A cross-sectional study

open access: yesPerspectives in Clinical Research, 2023
Background: Global evidence-based recommendations for hypertension management are periodically updated, and ensuring adherence to the guidelines is imperative.
S Shanmugapriya   +5 more
doaj   +1 more source

MANAGING TARGET COSTS AT THE DEVELOPMENT STAGE OF A PRODUCT

open access: yesJournal of Production Engineering, 2020
At the development stage of a product, target cost management has a significant effect on achievement and maintenance of product competitiveness in a given market and the desired target profit as the primary aim of production. Target cost management, i.e., target profit management, is performed by evaluating individual variations of a conceptual and ...
Vladimir Todić   +2 more
openaire   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

Transfering Target Excellence Overseas: Toward a Conceptual Framework of Global Target Cost Management [PDF]

open access: yes, 2002
Target cost management(TCM) has become a significant issue in off-shore bases of Japanese corporation in line with globalization of product development functions in recent years. This article, instead of discussing " whether it is transferable or not",
Okano, Hiroshi
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Medicaid managed care: how to target efforts to reduce costs [PDF]

open access: yesBMC Health Services Research, 2014
To be successful, cost control efforts must target Medicaid Managed Care (MMC) beneficiaries likely to incur high costs. The critical question is how to identify potential high cost beneficiaries with simple, reproducible, transparent, auditable criteria.
Charlson, Mary E   +4 more
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Economical Regulating Strategies Based on Enhanced EVM Model in Electric Substation Construction Projects

open access: yesEnergies
With the increasing demand for electricity in modern society, the scale of substation construction projects has greatly expanded, and the ever-increasing technical requirements have led to rising project costs year by year.
Hongyan Xin   +3 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Integration between Target Costing and Activity Based Costing and its Role in Rationalizing Investment Decisions : Case Study

open access: yesتنمیة الرافدین
Target costing and activity-based costing are cost management tools that support strategic cost management in addressing these challenges, especially since this requires integrating the two technologies.
Israa Yousif Thanoon
doaj   +1 more source

Home - About - Disclaimer - Privacy