Results 41 to 50 of about 382,266 (299)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Economical Regulating Strategies Based on Enhanced EVM Model in Electric Substation Construction Projects

Energies
With the increasing demand for electricity in modern society, the scale of substation construction projects has greatly expanded, and the ever-increasing technical requirements have led to rising project costs year by year.
Hongyan Xin, Zhengdong Wan, Yan Huang, Jinsong Zhang   +3 more
doaj   +1 more source

Medicaid managed care: how to target efforts to reduce costs [PDF]

BMC Health Services Research, 2014
To be successful, cost control efforts must target Medicaid Managed Care (MMC) beneficiaries likely to incur high costs. The critical question is how to identify potential high cost beneficiaries with simple, reproducible, transparent, auditable criteria.
Charlson, Mary E, Wells, Martin T, Kanna, Balavenkatesh, Dunn, Van, Michelen, Walid   +4 more
openaire   +2 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Cost modelling techniques for availability type service support contracts: a literature review and empirical study [PDF]

, 2009
Organised by: Cranfield UniversityThe research in this paper is focused on enhancing existing knowledge in cost estimation models at the bidding stage of service support contracts.
Datta, Partha Priya
core  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Integration between Target Costing and Activity Based Costing and its Role in Rationalizing Investment Decisions : Case Study

تنمیة الرافدین
Target costing and activity-based costing are cost management tools that support strategic cost management in addressing these challenges, especially since this requires integrating the two technologies.
Israa Yousif Thanoon
doaj   +1 more source

Cost management in the internal value chain of integrated application of activity-based costing, Kaizen concept and target costing [PDF]

Megatrend Revija, 2014
The objective of this paper is an effort to view the possibilities of integrated use of target costing, activity based costing and Kaizen concept in the internal value chain as the central link of the entire chain.
Pešić-Tomić Vesna, Andrijašević Maja   +1 more
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Sistemática de implementação do custeio-alvo na cadeia de suprimentos com o uso do desdobramento da função qualidade (QFD) [PDF]

, 2009
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Produção.O Custeio-alvo é importante no processo de integração da Cadeia de Suprimentos, pois é uma característica própria do ...
Lorandi, Joisse Antonio
core