Results 101 to 110 of about 2,123,261 (297)
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Competitive Pressure, Incentives and Managerial Rewards [PDF]
The paper examines the equilibrium relationship between managerial incentives and product market competition in imperfectly competitive industries.
Marcello D'Amato +2 more
core
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Trade costs and facilitation in APEC and ASEAN: Delivering the goods? [PDF]
This paper uses a new methodology to provide some first evidence on the overall level of trade costs in APEC and ASEAN. On average, APEC member economies have met the Shanghai target of a 5% reduction in trade costs over five years, but only just ...
Shepherd, Ben
core +1 more source
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
How to achieve the Kyoto Target in Belgium, modelling methodology and some results [PDF]
This paper discusses the methodology and some results to assess the means and costs of meeting the Kyoto target for Greenhouse gas emissions in Belgium. This target consists in reducing the emissions of Greenhouse gasses in 2008-2012 by 7.5% compared to ...
Denise Van Regemorter, Stef Proost
core
Delayed Action and Uncertain Targets. How Much Will Climate Policy Cost? [PDF]
Despite the growing concern about actual on-going climate change, there is little consensus about the scale and timing of actions needed to stabilise the concentrations of greenhouse gases.
Alessandra Sgobbi +3 more
core +3 more sources
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
The Costs of Inflexible Indexing: Avoiding the Adverse Fiscal Impacts of Lower Inflation [PDF]
A lively debate is underway about replacing Canada’s 2 percent inflation target with a target for lower inflation or a target for the price level itself when Canada’s inflation-control arrangement expires at the end of 2011.
Philippe Bergevin, William B.P. Robson
core
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source