Threat Perception, Policy Diffusion, and the Logic of Terrorist Group Designation [PDF]
Studies in Conflict and Terrorism, 2021 Many governments maintain lists of terrorist groups, imposing sanctions on designated organizations. However, the logic behind designation remains unclear. Furthermore, most studies focus on Western countries. This paper develops arguments for why attack
Mirna El Masri, B. J. Phillips
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Application of orphan drug designation to cancer treatments (2008–2017): a comprehensive and comparative analysis of the USA and EU [PDF]
BMJ Open, 2019 Objective To determine differences in the characteristics of cancer drugs designated as orphan drugs by the Food and Drug Administration (FDA) and European Medicines Agency (EMA).Design and setting Identification of all cancer drugs (initial or ...
Aaron S Kesselheim +1 more
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Utrecht Law Review, 2009 There is general agreement that representative and ecologically coherent networks of marine protected areas (MPAs) should be created to maintain biodiversity and to conserve specific species, habitats and ecological processes.
Harm Dotinga, Arie Trouwborst
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Are products with an orphan designation for oncology indications different from products for other rare indications? A retrospective analysis of European orphan designations granted between 2002-2012 [PDF]
Orphanet Journal of Rare Diseases, 2017 BackgroundOrphan designated medicinal products benefit from regulatory and economic incentives for orphan drug development. Approximately 40% of orphan designations target rare neoplastic disorders, referring to rare cancers.
K. Pauwels +7 more
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The MAP kinase pathway coordinates crossover designation with disassembly of synaptonemal complex proteins during meiosis [PDF]
eLife, 2016 Asymmetric disassembly of the synaptonemal complex (SC) is crucial for proper meiotic chromosome segregation. However, the signaling mechanisms that directly regulate this process are poorly understood.
Saravanapriah Nadarajan +13 more
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JAMMING COMPLEX FOR PRECISION WEAPON WITH SEMI-ACTIVE LASER-GUIDED SYSTEMS
Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019 The description and operation mode of the jamming complex for semi-active laser-guided systems, fixed at the high-precision weapon are added. The complex aims to detect the target designation pulse reflected from a target and generation false target ...
S. I. Rudikov
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Designation of Streptomycete 16S and 23S rRNA-based target regions for oligonucleotide probes [PDF]
Applied and Environmental Microbiology, 1991 The 16S and 23S rRNA of various Streptomyces species were partially sequenced and screened for the presence of stretches that could define all members of the genus, groups of species, or individual species.
E. Stackebrandt +4 more
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Robust designation of meiotic crossover sites by CDK-2 through phosphorylation of the MutSγ complex
bioRxiv, 2021 Crossover formation is essential for proper segregation of homologous chromosomes during meiosis. Here we show that C. elegans Cyclin-dependent kinase 2 (CDK-2) forms a complex with cyclin-like protein COSA-1 and supports crossover formation by promoting
Jocelyn Haversat +9 more
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Ligand recognition and activation of neuromedin U receptor 2
Nature Communications, 2022 Neuromedin U receptor 2 is an emerging attractive target for treating obesity. Here, a Cryo-EM structure of NmU-25–NMU2–Gi1 provides the structural basis for the designation of highly selective drugs.
Wenli Zhao +13 more
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ON THE PROBLEM OF FORMING THE APPEARANCE OF PROMISING UNMANNED AERIAL VEHICLES
Надежность и качество сложных систем, 2022 Background. The widespread use of unmanned aerial vehicles (UAVs) as individual products, and especially in the complex solution of a complex multi-purpose task, is provided by the development of technology and technology.
Thanh Long Nguen +2 more
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