Results 121 to 130 of about 18,258,763 (354)

Research on Lightweight Tracking of Small-Sized UAVs Based on the Improved YOLOv8N-Drone Architecture

open access: yesDrones
Traditional unmanned aerial vehicle (UAV) detection and tracking methods have long faced the twin challenges of high cost and poor efficiency. In real-world battlefield environments with complex backgrounds, occlusions, and varying speeds, existing ...
Yongjuan Zhao   +4 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Multiscale differential fractal feature with application to target detection

open access: yes, 2004
A multiscale differential fractal feature of an image is proposed and a small target detection method from complex nature clutter is presented. Considering the speciality that the fractal features of man-made objects change much more violently than that ...
Shi ZL(史泽林)   +2 more
core  

zhangpenglei/Target-Detection: Target-DetectionRelease

open access: yes
<p>Target-DetectionRelease</p ...
zhangpenglei
core   +1 more source

DTRFR: A Unified Detector for Diverse Target Detection in High-Spatial-Resolution Spaceborne Infrared Video

open access: yesRemote Sensing
Spaceborne infrared small-target detection plays a critical role in space-sky early warning, disaster rescue, and reconnaissance tracking, benefiting from all-time, all-weather, and wide-area monitoring capabilities.
Xiaoying Wu   +4 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

DNA methods for the detection of Phytophthora cinnamomi from soil [PDF]

open access: yes, 2006
This project assesses two aspects of DNA detection of Phytophthora species from soil samples. Firstly, a nested PCR protocol was established with both primary and nested PCR specific for P. cinnamomi detection. PCR amplification of P.
Anderson, Nari Michelle
core  

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