Results 151 to 160 of about 18,258,763 (354)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Pautomatic Sea Target Detection Based on Wavelet Transform

open access: yes, 2009
An effective automatic target detection algorithm based on wavelet transform,which takes advantage of the localization and the orientation of wavelet analysis,is proposed.The algorithm detects the target in the vertical component of the wavelet ...
Luo HB(罗海波), Pei LL(裴立力)
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

A neurobiological and computational analysis of target discrimination in visual clutter by the insect visual system. [PDF]

open access: yes, 2009
Some insects have the capability to detect and track small moving objects, often against cluttered moving backgrounds. Determining how this task is performed is an intriguing challenge, both from a physiological and computational perspective.
Wiederman, Steven
core  

Mamba-Infrared Small Target Detection: Multi-Context Hierarchical Aggregation Mamba for Robust Infrared Small Target Detection

open access: yesEngineered Science
Infrared small target detection (ISTD) plays a crucial role in applications such as security surveillance, maritime rescue, and satellite remote sensing.
Lingyan Ran   +3 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

A novel fluorescent sensitive assay for detection of differential T cell mediated lysis of multiple adherent target cells

open access: yes, 2006
There are few studies that have investigated T cell mediated lysis of adherent cells. We have developed a novel, rapid and sensitive fluorescent dye-swap assay that allows efficient detection of adherent target cell lysis.
Ardern-Jones, Michael   +3 more
core   +1 more source

Improved Multispectral Target Detection Using Target-Specific Spectral Reconstruction

open access: yesRemote Sensing
Hyperspectral sensors provide high spectral resolution, enabling accurate material discrimination and effective target detection. However, their practical use is constrained by limited spatial resolution and high acquisition costs.
Nicola Acito   +2 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

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