Results 271 to 280 of about 4,125,193 (296)

Pharmacological Target Engagement and Validation

2022
openaire   +1 more source

89Zr-Immuno-PET with Immune Checkpoint Inhibitors: Measuring Target Engagement in Healthy Organs

Cancers, 2023
Gerben J Zwezerijnen, Hanneke Pouw, Iris H C Miedema   +2 more
exaly  

Establishing and Validating Cellular Functional Target Engagement Assay for Selective IRAK4 Inhibitor Discovery.

SLAS Discovery, 2021
Jeremy P Presland, Jongwon Lim
exaly  

A call for better understanding of target engagement in Tau antibody development

Drug Discovery Today, 2022
Anton Bespalov, Leonard Khiroug
exaly  

High-Throughput Implementation of the NanoBRET Target Engagement Intracellular Kinase Assay to Reveal Differential Compound Engagement by SIK2/3 Isoforms

SLAS Discovery, 2020
Brian A Sparling, Antony Symons, Yanyan Tudor   +2 more
exaly  

The Cellular Thermal Shift Assay: A Novel Biophysical Assay for In Situ Drug Target Engagement and Mechanistic Biomarker Studies

Annual Review of Pharmacology and Toxicology, 2016
Pär Nordlund, Daniel Martinez Molina
exaly  

Quantitative, Wide-Spectrum Kinase Profiling in Live Cells for Assessing the Effect of Cellular ATP on Target Engagement

Cell Chemical Biology, 2018
Stefan Knapp, Rachel Friedman Ohana, Thomas Hanke   +2 more
exaly  

Target Engagement with Transcranial Current Stimulation

2021
Flavio Fröhlich, Rachel Force, Wei Angel Huang, Caroline Lustenberger, Trevor McPherson, Justin Riddle, Christopher Walker   +6 more
openaire   +1 more source

ENHANCEMENT OF KINASE TARGET ENGAGEMENT

2021
VASTA JAMES, ROBERS MATTHEW
openaire   +3 more sources

A Cell-Based Target Engagement Assay for the Identification of Cereblon E3 Ubiquitin Ligase Ligands and Their Application in HDAC6 Degraders

Cell Chemical Biology, 2020
Bo Wang, Ka Yang, Weiping Tang
exaly