Results 111 to 120 of about 22,960 (241)

Preventive role of rottlerin in endotoxin-induced uveitic glaucoma in rats

Future Journal of Pharmaceutical Sciences
Background Rottlerin is a natural polyphenolic compound obtained from dried ripe fruits of Mallotus philippinensis and is primarily used as a PKCδ inhibitor. The effectiveness of rottlerin was checked in the endotoxin-induced glaucoma models, focusing on
Nidhi Kumari, Ashmita Das, Nirdesh Kumar, Geeta Singh, Urvashi Jain, Amrita Singh, Surendra H. Bodakhe   +6 more
doaj   +1 more source

Selumetinib as a Target Therapy in Progressive Paediatric Low‐Grade Gliomas—Case Series (pLGG)

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background Optic pathway gliomas (OPGs) occur in 15%–20% of children with neurofibromatosis type 1 (NF1). While smaller gliomas may be only monitored, the current standard of care for symptomatic ones relies on chemotherapy, most commonly carboplatin and vincristine.
Laura Trapani, Giulia Gortani, Andrea Magnolato, Flora Maria Murru, Elisabetta Cattaruzzi, Laura Diplotti, Paola Michieletto, Silvia Giganti, Davide Zanon, Alessandra Maestro, Valentina Kiren, Egidio Barbi, Irene Bruno   +12 more
wiley   +1 more source

Effect of preservative removal from fixed-combination bimatoprost/timolol on intraocular pressure lowering: a potential timolol dose–response phenomenon

Clinical Ophthalmology, 2016
Jie Shen,1 Marina Bejanian2 1Department of Translational Sciences, 2Department of Ophthalmology Clinical Development, Allergan plc, Irvine, CA, USA Purpose: Many patients with glaucoma require combination therapies to achieve target intraocular ...
Shen J, Bejanian M
doaj  

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Prevalence and outcome of lens capsule disruption in routine canine cataract surgery: A retrospective study of 520 eyes (2012–2019)

Veterinary Ophthalmology, Volume 28, Issue 2, Page 141-149, March 2025.
Abstract Objective To investigate the prevalence and surgical outcome of lens capsule disruption (LCD) in dogs undergoing cataract removal. Animals studied Medical records of 924 eyes undergoing phacoemulsification were analyzed retrospectively. Procedures Routine cataract surgeries with or without LCD were included. Any LCD other than routine anterior
Amy L. M. M. Andrews, Christiane Kafarnik, Maria‐Christine Fischer   +2 more
wiley   +1 more source

The use of a “horizontal centrifugation protocol” to prepare autologous platelet‐rich fibrin membranes for corneal reconstruction surgery in dogs with complicated corneal ulcerations: A case series

Veterinary Ophthalmology, Volume 28, Issue 2, Page 175-189, March 2025.
Abstract Objective The purpose of this case series was to describe the effect of autologous PRF membrane for corneal reconstruction surgery in dogs. PRF membranes made from two healthy dogs unrelated to the current case series were used for PRF histologic analyses. Animals Seven dogs with complicated corneal ulcerations. Procedure A complete ophthalmic
Louise Baadsgaard Bruun, Tommy A. Waskiw Hardon, Anne K. Havnsøe Krogh, Klaus Qvortup, Steffen Heegaard, Annemarie Thuri Kristensen, Michala de Linde Henriksen   +6 more
wiley   +1 more source

Vision outcomes in dogs with primary glaucoma surgically treated with lensectomy and endolaser cyclophotocoagulation after an Ahmed valve gonioimplantation failure

Veterinary Ophthalmology, Volume 28, Issue 2, Page 207-217, March 2025.
Abstract Objective The aim of this study was to retrospectively evaluate vision outcomes of dogs with primary angle closure glaucoma (PACG) that underwent Ahmed valve gonioimplantation (AVG) followed by lensectomy and endolaser cyclophotocoagulation (ECP) with or without bleb resection after AVG failure.
Bactelius Turicea, Christian L. Munevar, Sydney G. Edwards, Lana L. Linton   +3 more
wiley   +1 more source

Micropulse transscleral cyclophotocoagulation in canine glaucoma: A retrospective study evaluating sweep velocity

Veterinary Ophthalmology, Volume 28, Issue 2, Page 293-305, March 2025.
Abstract Objective To report preliminary results of MP‐TSCP in canine patients with glaucoma while evaluating sweep velocity, treatment efficacy, and safety utilizing standardized surgical parameters. Animal studied Client‐owned dogs that underwent MP‐TSCP at a veterinary referral hospital. Procedure Medical records of 19 eyes (14 dogs) treated with MP‐
Valeria Benitez‐Vera, Dineli Bras, Fabiano Montiani‐Ferreira   +2 more
wiley   +1 more source

The Impact of Achieving Target Intraocular Pressure on Glaucomatous Retinal Nerve Fiber Layer Thinning in a Treated Clinical Population. [PDF]

Am J Ophthalmol
Pham AT, Bradley C, Hou K, Herbert P, Boland MV, Ramulu PY, Yohannan J.   +6 more
europepmc   +1 more source

Techniques for subretinal injections in animals

Veterinary Ophthalmology, Volume 28, Issue 2, Page 506-518, March 2025.
Abstract Subretinal injections are not commonly performed during clinical treatment of animals but are frequently used in laboratory animal models to assess therapeutic efficacy and safety of gene and cell therapy products. Veterinary ophthalmologists are often employed to perform the injections in the laboratory animal setting, due to knowledge of ...
Ryan F. Boyd, Simon M. Petersen‐Jones
wiley   +1 more source