Results 131 to 140 of about 6,846,778 (296)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Lightweight air-to-air unmanned aerial vehicle target detection model

Scientific Reports
The rapid expansion of the drone industry has resulted in a substantial increase in the number of low-altitude drones, giving rise to concerns regarding collision avoidance and countermeasure strategies among these unmanned aerial vehicles.
Qing Cheng, Yazhe Wang, Wenjian He, Yu Bai   +3 more
doaj   +1 more source

YOLOv8-SC: an improved seafood target-detection model

European Journal of Remote Sensing
The advancement of convolutional neural networks has significantly enhanced autonomous underwater fishing. This study introduces YOLOv8-SC, a lightweight model designed for detecting valuable seafood and sea cucumbers in aquatic robots with limited ...
Zhaofeng Cong, Fusheng Yu
doaj   +1 more source

Revenue Targeting in Fisheries: The Case of Hawaii Longline Fishery [PDF]

We apply the target revenue model, a version of prospect theory, to investigate how fishermen adjust their trip length to changes in daily revenue. The key finding is that certain groups of fishermen seem more likely to behave according to the target ...
Leung, PinngSun, Nguyen, Quang
core   +1 more source

Models without a Target

Artefactos, 2018
It is frequently acknowledged that some scientific models do not have a target. In that case, it is not clear how surrogative reasoning is possible. In this article I contend that every model has a target. I argue that targets should not be identified with selected phenomena or with selected portions or aspects of the real world.
openaire   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Velar-vowel coarticulation in a virtual target model of stop production. [PDF]

J Phon, 2016
Frisch SA, Wodzinski SM.
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Radiosensitivity and relative biological effectiveness based on a generalized target model. [PDF]

J Radiat Res, 2017
Zhao L, Wu D, Mi D, Sun Y.
europepmc   +1 more source