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Model organisms and target discovery
Drug Discovery Today: Technologies, 2004The wealth of information harvested from full genomic sequencing projects has not generated a parallel increase in the number of novel targets for therapeutic intervention. Several pharmaceutical companies have realized that novel drug targets can be identified and validated using simple model organisms.
Marco, Muda, Sean, McKenna
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Automating ground-fixed target modeling with the smart target model generator
SPIE Proceedings, 2007The Smart Target Model Generator (STMG) is an AFRL/MNAL sponsored tool for generating 3D building models for use in various weapon effectiveness tools. These tools include tri-service approved tools such as Modular Effectiveness/Vulnerability Assessment (MEVA), Building Analysis Module in Joint Weaponeering System (JWS), PENCRV3D, and WinBlast.
D. Verner, R. Dukes
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Homology Modeling of Protein Targets with MODELLER
2019Homology modeling is a computational approach to generate three-dimensional structures of protein targets when experimental data about similar proteins are available. Although experimental methods such as X-ray crystallography and nuclear magnetic resonance spectroscopy successfully solved the structures of nearly 150,000 macromolecules, there is still
Gabriela, Bitencourt-Ferreira +1 more
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Proceedings of 1994 IEEE National Radar Conference, 2002
Full-scale measurement and mathematical prediction are widely accepted as being valid means of obtaining target radar cross section (RCS) data. Sub-scale modelling, however, is viewed with suspicion in some quarters. By comparison with full-scale and predicted data, this paper demonstrates the validity of the technique, and the important role that it ...
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Full-scale measurement and mathematical prediction are widely accepted as being valid means of obtaining target radar cross section (RCS) data. Sub-scale modelling, however, is viewed with suspicion in some quarters. By comparison with full-scale and predicted data, this paper demonstrates the validity of the technique, and the important role that it ...
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Multimodal target prediction model
CHI '14 Extended Abstracts on Human Factors in Computing Systems, 2014This paper presents a Neural Network based model that can be used to predict pointing target for both physical and situational impairment. The model takes different trajectory profiles like velocity, acceleration and bearing of movement as input parameters and based on that predicts next pointing target.
Pradipta Biswas, Patrick Langdon
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Modelling Cued-Target Recall Using Quantum Inspired Models of Target Activation
2016This article presents and evaluates Quantum Inspired models of Target Activation using Cued-Target Recall Memory Modelling over multiple sources of Free Association data. Two components were evaluated: Whether Quantum Inspired models of Target Activation would provide a better framework than their classical psychological counterparts and how robust ...
Galea, David, Bruza, Peter
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High Frequency Radar Target Modeling.
1995Abstract : This report contains the theories behind the commonly accepted electromagnetic techniques used for Radar Cross Section (RCS) prediction and enumerates the prevailing computer models which characterize RCS for high-frequency complex targets. (MM)
Fred W. Sedenquist, Virginia C. Monk
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Topological DNA target size model
Radiation and Environmental Biophysics, 1990This study presents a model that explains the difference in radiosensitivity between dividing and resting mammalian non-lymphoid tissue cells (liver, kidney, respiratory tract, muscle cells, neurons), based on the topological organization of DNA. In dividing cells, the target for radiation might be identified in replicon clusters or domains (7 X 10(8 ...
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Analytic Radar Target Modeling
1972Abstract : The report studies the electromagnetic radar scattering parameters for a complex airborne target at high frequencies. The components of the target are modeled by simple geometrical shapes including ellipsoids, elliptical plates, ogives, and semi-individual component are derived in terms of simple analytical functions.
C. A. Chuang, S. W. Lee, R. Mittra
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