Blood pressure variability and target organ damage regression in hypertension
The study by Triantafyllidi et al. supports the view that regression of subclinical cardiac damage requires an effective 24‐hour blood pressure (BP) control along with a reduction in BP variability and suggests that the assessment of BPV and its ...
Cesare Cuspidi +2 more
doaj +1 more source
Targeting Epoxides for Organ Damage in Hypertension [PDF]
Epoxyeicosatrienoic acids (EETs) are synthesized from arachidonic acid and EETs have a number of beneficial cardiovascular actions. This has led to the concept that EETs and its metabolic pathway can be therapeutically targeted for hypertension and other cardiovascular diseases.
openaire +2 more sources
CD2 CIRCADIAN BLOOD PRESSURE PROFILE AND TARGET ORGAN DAMAGE
The 24-hour brachial ambulatory blood pressure measurement (ABPM) has the unique ability to provide information on 24-hour averaged blood pressure (BP), on nocturnal BP and day–night BP changes, as well as on 24-hour BP variability, which all provide ...
Agnieszka Bednarek
doaj +1 more source
Obesity and target organ damage: diabetes [PDF]
Obesity is an important risk factor for the development of type 2 diabetes. The increasing incidence of obesity accounts in large part for the emergence of type 2 diabetes. Drug treatment of hyperglycaemia and hypertension lowers the risk of diabetic complications, but many of these treatments, including sulphonylureas, insulin and beta-blockers, are ...
openaire +2 more sources
Hypertensive Target-Organ Damage in the Very Elderly [PDF]
In people aged >80 years, the so-called very elderly, there is uncertainty about the relation between hypertension and cardiovascular morbidity. The aims of this study were to investigate whether hypertension in people aged >80 years is associated with target-organ damage, over and above the effects of age, and to determine whether ...
Cianán, O'Sullivan +5 more
openaire +2 more sources
Cardiac and Vascular Target Organ Damage in Pediatric Hypertension
Atherosclerosis begins in youth and is associated with the presence of numerous modifiable cardiovascular (CV) risk factors, including hypertension. Pediatric hypertension has increased in prevalence since the 1980s but has plateaued in recent years ...
Michael Khoury, Elaine M. Urbina
doaj +1 more source
Effect of cofactors on NAFLD/NASH and MAFLD. A paradigm illustrating the pathomechanics of organ dysfunction [PDF]
Primary nonalcoholic fatty liver disease (NAFLD) is bi-directionally associated with the metabolic syndrome and its constitutive features (“factors”: impaired glucose disposal, visceral obesity, arterial hypertension, and dyslipidemia).
Singal, Ashwani K. +3 more
core
MICROALBUMINURIA IN SUBCLINICAL TARGET ORGAN DAMAGE AND ITS CORRELATION TO CREATININE CLEARANCE RATIO IN HYPERTENSION [PDF]
Background: Target organ damage takes place early in course of hypertension. But, despite this, the disease remains inadequately controlled in majority of patients partly because of its asymptomatic nature.
G B Doddamani, Joby Thomas Mammen
core +4 more sources
Office blood pressure measurement in the 21st century [PDF]
Measurement of blood pressure (BP) using the auscultatory method must follow specific rules and conditions to be reliable. Nonetheless, these requirements are often not followed in clinical practice, resulting in inaccurate BP readings.
Staessen, Jan A. +2 more
core +1 more source
Genotoxicity of nitroso compounds and sodium dichromate in a model combining organ cultures of human nasal epithelia and the comet assay [PDF]
Genotoxic effects of xenobiotics are a possible step in tumor initiation in the mucosa of the upper aerodigestive tract. Using the comet assay, detecting genotoxicity in human tissue has been restricted to single incubations in vitro, but in vivo most ...
Bergner, Albrecht +7 more
core +1 more source

