Results 91 to 100 of about 8,510,768 (280)

Proposal for a unified nomenclature for target‐site mutations associated with resistance to fungicides

open access: yesPest Management Science, 2016
AbstractEvolved resistance to fungicides is a major problem limiting our ability to control agricultural, medical and veterinary pathogens and is frequently associated with substitutions in the amino acid sequence of the target protein. The convention for describing amino acid substitutions is to cite the wild‐type amino acid, the codon number and the ...
Mair, Wesley   +17 more
openaire   +8 more sources

EPSPS target site mechanisms confer glyphosate resistance in Arctotheca calendula [PDF]

open access: yes
BACKGROUND: The first case of glyphosate resistance was reported in a capeweed population from Western Australia in our previous study. This current study investigates the resistance mechanisms in the population.
Han, Heping   +5 more
core   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Subgenomic Distribution and Herbicide Cross‐Resistance of ALS Gene Mutations in Allohexaploid Echinochloa crus‐galli

open access: yesPlant Direct
Herbicide target site resistance in polyploid species is more complex than in diploids due to potential subgenome interactions. This study characterized mutations in the ALS gene across distinct subgenomes of hexaploid Echinochloa crus‐galli and ...
Luan Cutti   +7 more
doaj   +1 more source

Contrasting levels of genetic predictability in the evolution of resistance to major classes of fungicides

open access: yes, 2021
The evolution of resistance has been seen across all major classes of xenobiotics, including antimicrobial drugs and agricultural pesticides. This repeated emergence of resistance is a case of phenotypic parallel evolution, but often the parallelism ...
Hawkins, N. J.   +5 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

An evolutionary-physiology perspective on the emergence of non-target-site herbicide resistance. [PDF]

open access: yesJ Exp Bot
Integrating evolutionary physiology with experimental evolution shows how transient herbicide stress responses can become stable heritable resistance traits, improving the prediction and management of rapid weed adaptation.
He L, Liu Y, Wang A, Ghanizadeh H.
europepmc   +3 more sources

The presence of two different target-site resistance mechanisms in individual plants of Alopecurus myosuroides Huds., identified using a quick molcular test for the characterisation of six ALS and seven ACCase SNPs

open access: yes, 2012
BACKGROUND Target-site resistance to ALS- and ACCase-inhibiting herbicides in the grass weed Alopecurus myosuroides is associated with well-characterised allelic variants encoding ALS- and ACCase-based resistance.
Moss, S. R.   +6 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Insight into the herbicide resistance patterns in Lolium rigidum populations in Tunisian and Moroccan wheat regions

open access: yesFrontiers in Plant Science
Rigid ryegrass (Lolium rigidum Gaud.) is one of the most troublesome weeds in Moroccan and Tunisian cereal crop fields. In total, 19 rigid ryegrass field populations were randomly selected in northern wheat crop areas of Morocco and Tunisia to examine ...
Zakia El-Mastouri   +4 more
doaj   +1 more source

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