Results 161 to 170 of about 573,850 (267)

Brain-Targeted Delivery of Phenformin Using Phospholipid and Non-Phospholipid Vesicles for SHH Medulloblastoma. [PDF]

Nanomaterials (Basel)
Di Magno L, Rinaldi F, Campea L, Della Rocca G, Forte J, D'Intino E, Cairoli S, Goffredo BM, Carafa M, Del Favero E, Marianecci C, Canettieri G.   +11 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Targeted delivery of gemcitabine to lung cancer cells <i>via</i> a hyaluronic acid-based nanoplatform. [PDF]

RSC Adv
Yu F, Cao J, Fan X, Gao J, Liu G, Lin C, Zhu Y, Wang Q.   +7 more
europepmc   +1 more source

Magnet-Targeted Delivery and Imaging [PDF]

, 2016
Patrick, PS, Pankhurst, QA, Payne, C, Kalber, TL, Lythgoe, MF   +4 more
openaire   +2 more sources

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Palladium-Catalyzed Intramolecular Cross-Dehydrogenative Coupling: Synthesis of Fused Imidazo[1,2‑a]pyrimidines and Pyrazolo[1,5‑a]pyrimidines

ACS Omega, 2017
Siva K. Reddy Kotla, Jaya Kishore Vandavasi, Jeh-Jeng Wang, Keykavous Parang, Rakesh K. Tiwari   +4 more
doaj   +1 more source

Liposome-Based Photodynamic Therapy for Breast Cancer: Innovations in Targeted Delivery, Combination Strategies, and Clinical Translation. [PDF]

Int J Mol Sci
Banu N, de la Rosa E, Saeed MA, Salas P, Panikar SS.   +4 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Targeted delivery of glucocerebrosidase to lysosomes: The LYSOTAC (LYSOsome-TArgeting Chimera) technology. [PDF]

Asian J Pharm Sci
Kim HY, Choi EN, Lee GE, Yoon S, Mun SR, Jung EJ, Kim M, Lim H, Kang YJ, Park WJ, Kwon YT, Park JW.   +11 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source