Deep Learning Improves Robustness of Voxelwise Kinetic Modeling for Hyperpolarized Carbon‐13 MRI
ABSTRACT Purpose To evaluate whether deep learning improves the robustness of voxelwise kinetic parameter estimation from hyperpolarized (HP) 13C MRI compared with nonlinear least‐squares (NLLS) fitting. Methods A hybrid neural network (NN) was trained on synthetic pyruvate/lactate time courses generated from an open‐system two‐compartment HP 13C ...
Kofi Deh +5 more
wiley +1 more source
Pain control according to the periprostatic nerve block site in magnetic resonance imaging/transrectal targeted prostate biopsy. [PDF]
Yoo JW, Koo KC, Chung BH, Lee KS.
europepmc +1 more source
A transition zone enriched WIF1+ basal cell subtype is associated with benign prostatic hyperplasia
Abstract The cellular composition and disease susceptibilities of the distinct zones of the human prostate remain incompletely understood. Benign prostatic hyperplasia (BPH) is a common condition that causes widespread morbidity and is nearly exclusively localized to the transition zone (TZ).
Rulin Wang +20 more
wiley +1 more source
Natural History of PI‐RADS 3 Lesions on Serial Prostate mpMRI
ABSTRACT Objective PI‐RADS 3 lesions on prostate multiparametric MRI (mpMRI) are indeterminate findings with debated management. We evaluated their radiologic evolution on follow‐up mpMRI and correlated imaging changes with biopsy outcomes. Methods We retrospectively identified 166 men with at least one PI‐RADS 3 lesion on initial mpMRI and at least ...
Tomer Bashi +13 more
wiley +1 more source
ABSTRACT Background Intermediate‐risk prostate cancer (IR‐PCa) is a heterogeneous disease with variable clinical outcomes despite established risk classification. We evaluated whether pretreatment tumor apparent diffusion coefficient (ADC) derived from multiparametric MRI was associated with long‐term outcomes and provided additional prognostic ...
Cem Onal +4 more
wiley +1 more source
Abstract Patients with recurrent high‐grade glioma (rHGG) have a poor prognosis with median progression‐free survival (PFS) of <7 months. Responses to treatment are heterogenous, suggesting a clinical need for prognostic models. Bayesian data analysis can exploit individual patient follow‐up imaging studies to adaptively predict the risk of progression.
Daniel J. Glazar +5 more
wiley +1 more source
Advances in new ultrasound technologies in targeted prostate biopsy (Review). [PDF]
Jin T, Wang L, Zheng S.
europepmc +1 more source
Transperineal versus transrectal multi-parametric magnetic resonance imaging fusion targeted prostate biopsy. [PDF]
Rabah D +6 more
europepmc +1 more source
Mechanistic Learning for Predicting Survival Outcomes in Head and Neck Squamous Cell Carcinoma
ABSTRACT We employed a mechanistic learning approach, integrating on‐treatment tumor kinetics (TK) modeling with various machine learning (ML) models to address the challenge of predicting post‐progression survival (PPS)—the duration from the time of documented disease progression to death—and overall survival (OS) in Head and Neck Squamous Cell ...
Kevin Atsou +4 more
wiley +1 more source
Clinical significance of quantification of perineural cancer invasion on MRI-targeted prostate biopsy. [PDF]
Ramineni M, Wang Y, Miyamoto H.
europepmc +1 more source

