Results 41 to 50 of about 56,415 (302)
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
The paper presents the results of an investigation into the kinetics of catalytic hydrogenation of vacuum residue at temperatures of 380, 400 and 420 °C and different durations, ranging from 30 to 70 min, using a nanocatalyst containing the active metals
Nazerke Balpanova +5 more
doaj +1 more source
Análisis e interpretación de entornos situacionales mediante el Análisis Reticular del Discurso
El contenido principal del artículo se orienta a analizar conjuntos de conceptos que se vinculan cognitivamente entre sí para construir entornos semánticamente conectados mediante el Análisis Reticular del Discurso (ARD). El ARD se inspira en los modelos
Carlos Lozares +2 more
doaj +1 more source
Collagen hydrolysate is evaluated as a sustainable binder for MgO‐C refractories. Its thermally induced cross‐linking and gas release lead to expansion and cracking in large bricks, but tailored batches with lignin, recyclates, or fine graphite improve the gas release while thermal treatment and stability.
Till M. J. Stadtmüller +8 more
wiley +1 more source
This paper presents a new microstrip implantable antenna (MIA) design based on the two-arm rectangular spiral (TARS) element for ISM band (Industrial, Scientific, and Medical 2.4–2.48 GHz) biotelemetric sensing applications.
Mustafa Hikmet Bilgehan Ucar, Erdem Uras
doaj +1 more source
Spatial scaling of forest soil microbial communities across a temperature gradient. [PDF]
Temperature is an important correlate of global patterns of biodiversity, yet the mechanisms driving these relationships are not well understood. Taxa-area relationships (TARs) have been intensively examined, but the effects of temperature on TARs ...
Allen +70 more
core +1 more source
This study develops sustainable MgO–C refractories using recycled materials and eco‐friendly fructose–tannin binders. The enhanced performance of citric acid as a cross‐linker and functional additives on mechanical and thermomechanical properties was examined. Characterization included strength tests, immersion trials, and microstructural and inclusion
Dinesh K. Gunasekar +7 more
wiley +1 more source
Dense Nanofibrillar Collagen–Silica Hybrids with High Strength and ECM‐Mimetic Tissue Integration
Dense nanofibrillar collagen–silica hybrids are engineered by synchronizing collagen fibrillogenesis with silica condensation, producing printable scaffolds that unexpectedly approach native extracellular matrix organization and strength. These cell‐free constructs guide endogenous cell‐infiltration, enable localized matrix remodeling, and integrate ...
Norein Norein +7 more
wiley +1 more source
A two‐nanosensor electrochemical strategy quantitatively distinguishes reactive oxygen species (ROS) in stress granules (SGs) from catecholamines in vesicles inside living cells. Chronic SGs formed under prolonged stress show elevated ROS and slower release, consistent with SG aging, and promote neurotransmitter loading likely through vesicle fusion ...
Hui Gu +3 more
wiley +2 more sources

