Results 41 to 50 of about 56,761 (299)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

TAR IN THE BLOOD. [PDF]

open access: yesThe Lancet
n ...
openaire   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

open access: yesAdvanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim   +6 more
wiley   +1 more source

Análisis e interpretación de entornos situacionales mediante el Análisis Reticular del Discurso

open access: yesAthenea Digital, 2020
El contenido principal del artículo se orienta a analizar conjuntos de conceptos que se vinculan cognitivamente entre sí para construir entornos semánticamente conectados mediante el Análisis Reticular del Discurso (ARD). El ARD se inspira en los modelos
Carlos Lozares   +2 more
doaj   +1 more source

The distribution of Transverse Aeolian Ridges on Mars [PDF]

open access: yes, 2008
not ...
Balme, M. R.   +3 more
core  

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen   +6 more
wiley   +1 more source

Fully Wireless and Flexible Valves for Multiplexed and Prolonged Intravesical Liquid Release

open access: yesAdvanced Healthcare Materials, EarlyView.
A fundamental mechanism for the simultaneous control of multiple magnetic valves is reported in a miniature soft robotic patch for intravesical drug delivery, enabling fully wireless and programmable liquid release. Integrated with a bioadhesive interface and induction‐coupling‐based liquid volume sensing, the soft robotic patch is promising to enable ...
Boyang Xiao   +5 more
wiley   +1 more source

Radiographic Analysis of Total Ankle Replacements

open access: yesFoot & Ankle Orthopaedics, 2018
Category: Ankle Arthritis Introduction/Purpose: Total ankle replacements (TAR) are an increasingly common treatment for end-stage ankle arthritis but evidence on optimal alignment is not as well-established as in the hip and knee arthroplasty literature.
Vu (Brian) Le MD, FRCSC   +6 more
doaj   +1 more source

A Compact Modified Two-Arm Rectangular Spiral Implantable Antenna Design for ISM Band Biosensing Applications

open access: yesSensors, 2023
This paper presents a new microstrip implantable antenna (MIA) design based on the two-arm rectangular spiral (TARS) element for ISM band (Industrial, Scientific, and Medical 2.4–2.48 GHz) biotelemetric sensing applications.
Mustafa Hikmet Bilgehan Ucar, Erdem Uras
doaj   +1 more source

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